Results 111 to 120 of about 8,038,699 (404)
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Examining HPO by organ and system to facilitate practical use by clinicians
Genomics & InformaticsThe Human Phenotype Ontology (HPO) is widely used for annotating clinical text data, and sufficient annotation is crucial for the effective utilization of clinical texts.
Eisuke Dohi +4 more
doaj +1 more source
Crystals, 2019 Interfaces in heterostructures of crystalline materials could strongly affect the slip of dislocations. Such interfaces have become one of the most popular methods to tailor material strength and ductility.
Zhibo Zhang +5 more
doaj +1 more source
Materials databases: the need for open, interoperable databases with standardized data and rich metadata [PDF]
Adv. Theory Simul., 2019, 2, 1900131, 2019 Driven by the recent rapid increase in the number of materials databases published (open and commercial), I discuss here some perspectives on the growing need for standardized, interoperable, open databases. The field of computational materials discovery is quickly expanding, and recent advances in data mining, high throughput screening, and machine ...
arxiv +1 more source
The InterPro protein families and domains database: 20 years on
Nucleic Acids Res., 2020 The InterPro database (https://www.ebi.ac.uk/interpro/) provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites.
Matthias Blum +32 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause +2 more
wiley +1 more source
BMC Medical Informatics and Decision MakingBackground Virtual Gene Panels (VGP) comprising disease-associated causal genes are utilized in the diagnosis of rare genetic diseases to evaluate candidate genes identified by whole-genome and whole-exome sequencing.
Jaemoon Shin +3 more
doaj +1 more source
The Meaning of Null in Databases and Programming Languages [PDF]
arXiv, 2016 The meaning of null in relational databases is a major source of confusion not only among database users but also among database textbook writers. The purpose of this article is to examine what database nulls could mean and to make some modest suggestions about how to reduce the confusion.
arxiv
Extensible Database Simulator for Fast Prototyping In-Database Algorithms [PDF]
arXiv, 2022 With the rapid increasing of data scale, in-database analytics and learning has become one of the most studied topics in data science community, because of its significance on reducing the gap between the management and the analytics of data. By extending the capability of database on analytics and learning, data scientists can save much time on ...
arxiv
Molecular signatures database (MSigDB) 3.0
Bioinform., 2011 MOTIVATION Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data.
A. Liberzon +5 more
semanticscholar +1 more source