Results 151 to 160 of about 6,912,826 (303)

Medical big data value creation: Role of the hospital-based research database

Journal of the Formosan Medical Association, 2023
Yen-Yun Yang, Yi-Chen Juan, Yi-Chia Lee
doaj   +1 more source

Comparing the performance of narrow vs. broad search strategies when using machine learning-based software for title/abstract screening. [PDF]

J Med Libr Assoc
Swab M.
europepmc   +1 more source

Database Integrity [PDF]

The Computer Journal, 1976
openaire   +2 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

ADHD medications and drug withdrawal: A pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database. [PDF]

PCN Rep
Ebina T, Iwamoto K, Ikeda M.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Operationalization of Severe Maternal Morbidity surveillance in administrative databases of the Brazilian public and private health systems: Brazil 2015-2022. [PDF]

PLoS One
Domingues RMSM, Dias MAB, Guillen LCT, Pinheiro RS, Saraceni V, Coeli CM.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Peatland Mid-Infrared Database. [PDF]

Sci Data
Teickner H, Agethen S, Berger S, Boelsen RI, Borken W, Bragazza L, Broder T, De La Cruz FB, Diaconu AC, Dise NB, Drollinger S, Estop-Aragonés C, Gałka M, Martí M, Glatzel S, Groß J, Harris L, Heffernan L, Hodgkins SB, Hömberg-Grandjean A, Hoppe H, Kleinebecker T, Knierzinger W, Liu H, Mathijssen P, Mollmann C, Schuster W, Närtker L, Olefeldt D, Pancotto V, Pelletier N, Reuter H, Robroek B, Svensson BH, Talbot J, Thompson L, Worrall F, Yu ZG, Knorr KH.   +38 more
europepmc   +1 more source