Results 141 to 150 of about 6,201,586 (306)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Intellectual Creation in Database: A Superfluous Test?
, 2013 369-376Prior to amendment of Section 8(1)(b) of the Malaysian Copyright Act 1987 in the year 2000, copyright protection was conferred to a database product, provided that sufficient effort had been used in the making of the work.
Manap, Nazura Abdul +3 more
core
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
DB[11]Database System Development Lifecycle
, 2012 [[abstract]]Database System Development ...
王學亮
core
An Interoperable Cartographic Database
Kartografija i Geoinformacije, 2007 The concept of producing a prototype of interoperable cartographic database is explored in this paper, including the possibilities of integration of different geospatial data into the database management system and their visualization on the Internet ...
Slobodanka Ključanin, Zdravko Galić
doaj
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Response to “Medical big data value creation: Role of the hospital-based research database”
Journal of the Formosan Medical Association, 2023 Tsung-Hsi Wang +2 more
doaj +1 more source
TECHNOLOGY OF DYNAMIC DATABASES CREATION WITH THE ENCLOSED STRUCTURES IN MS EXCEL
Ìнформаційні технології в освіті, 2012 In work questions of use of spreadsheets MS Excel for dynamic database creation with the enclosed structures are examined.
L.V. Kravtsova +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source