Results 111 to 120 of about 16,551,161 (356)

GAC. A methodology for creating dynamic websites

open access: yesIngeniería e Investigación, 2005
This paper presents a novel website methodology. The methodology is suitable for developing medium-sized websites and web applications as it is inspired by brainstormming and using mind maps.
Jean Pierre Charalambos   +2 more
doaj  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Design of a phonetic corpus for speech recognition in catalan [PDF]

open access: yes, 1998
In this paper, we present the design of a corpus for speech recognition to be used for the recording of a speech database in Catalan. A previous database in Spanish was the reference in setting the specifications about the characteristics of the ...
Esquerra Llucià, Ignasi   +3 more
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Design of the data-driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania [PDF]

open access: yesComputational Ecology and Software
This study presents a design of a Data-Driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania.
Ambokile Okey   +2 more
doaj  

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