Results 111 to 120 of about 17,028,074 (314)
Information Research: An International Electronic Journal, 1999 In August 1998 an international workshop on validation, verification and integrity issues of expert and database systems was held in Vienna in conjunction with the Ninth Conference on Database and Expert Systems Applications (DEXA'98). This paper reports
T. Bench-Capon, et al.
doaj
Antipatterns in Database Design
Открытое образование (Москва)The purpose of the study is to adapt the antipattern method to improve the effectiveness of teaching students in the fields of “Applied Informatics”, “Information Systems and Technologies”, “Software Engineering” to the principles and techniques of ...
S. M. Shcherbakov +3 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Scientific DataTime-course transcriptome expression data were constructed for four parts of the silk gland (anterior, middle, and posterior parts of the middle silk gland, along with the posterior silk gland) in the domestic silkworm, Bombyx mori, from days 0 to 7 of ...
Yudai Masuoka +7 more
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Synthesis using speaker adaptation from speech recognition DB [PDF]
, 2010 This paper deals with the creation of multiple voices from a Hidden Markov Model based speech synthesis system (HTS). More than 150 Catalan synthetic voices were built using Hidden Markov Models (HMM) and speaker adaptation techniques.
Bonafonte Cávez, Antonio +2 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Design of the data-driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania [PDF]
Computational Ecology and SoftwareThis study presents a design of a Data-Driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania.
Ambokile Okey +2 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
HKPocket: human kinase pocket database for drug design
BMC Bioinformatics, 2019 Background The kinase pocket structural information is important for drug discovery targeting cancer or other diseases. Although some kinase sequence, structure or drug databases have been developed, the databases cannot be directly used in the kinase ...
Huiwen Wang +5 more
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