Results 121 to 130 of about 3,236,092 (351)

Potentially Polluting Marine Sites GeoDB: An S-100 Geospatial Database as an Effective Contribution to the Protection of the Marine Environment [PDF]

open access: yes, 2012
Potentially Polluting Marine Sites (PPMS) are objects on, or areas of, the seabed that may release pollution in the future. A rationale for, and design of, a geospatial database to inventory and manipu-late PPMS is presented.
Alexander, Lee   +2 more
core   +3 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

J2EE application for clustered servers : focus on balancing workloads among clustered servers : a thesis presented in partial fulfilment of the requirements for the degree of Master of Information Science in Computer Science at Massey University, Albany, New Zealand [PDF]

open access: yes, 2006
J2EE has become a de facto platform for developing enterprise applications not only by its standard based methodology but also by reducing the cost and complexity of developing multi-tier enterprise applications.
Chen, Xi
core  

Design of the data-driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania [PDF]

open access: yesComputational Ecology and Software
This study presents a design of a Data-Driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania.
Ambokile Okey   +2 more
doaj  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Report on the 1st International Workshop on Validation, Verification and Integrity Issues of Expert and Database Systems

open access: yesInformation Research: An International Electronic Journal, 1999
In August 1998 an international workshop on validation, verification and integrity issues of expert and database systems was held in Vienna in conjunction with the Ninth Conference on Database and Expert Systems Applications (DEXA'98). This paper reports
T. Bench-Capon, et al.
doaj  

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