Results 131 to 140 of about 16,551,161 (356)

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

A database design methodology and tool for information systems [PDF]

, 1985
Roger King, Dennis McLeod
openalex   +1 more source

Data Mining the SDSS SkyServer Database

, 2002
An earlier paper (Szalay et. al. "Designing and Mining MultiTerabyte Astronomy Archives: The Sloan Digital Sky Survey," ACM SIGMOD 2000) described the Sloan Digital Sky Survey's (SDSS) data management needs by defining twenty database queries and twelve ...
Gray, Jim, Kunszt, Peter Z., Slutz, Don, Stoughton, Christopher, Szalay, Alex S., Thakar, Ani R., vandenBerg, Jan   +6 more
core  

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

THE OBJECTUAL DATABASE DESIGN FOR A VIRTUAL STORE [PDF]

Annals of the University of Oradea: Economic Science, 2010
Nowadays, the most systems on the Internet are using databases. These databases are relational and normalized. Although the tables of the relational model itself does not have a behaviour in context object, though the diagrams uses different methods.
Avornicului Constantin, Avornicului Mihai-Constantin, Popa Silviu   +2 more
doaj  

A formal approach to the definition and the design of conceptual schemata for databased systems [PDF]

, 1982
Carlo Zaniolo, Michel A. Melkaoff
openalex   +1 more source

Using UMLS for electronic health data standardization and database design. [PDF]

J Am Med Inform Assoc, 2020
Reimer AP, Milinovich A.
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The effect of target applications on the design of database machines [PDF]

, 1981
Paula Hawthorn
openalex   +1 more source

A UK-wide British Society of Thoracic Imaging COVID-19 imaging repository and database: design, rationale and implications for education and research. [PDF]

Clin Radiol, 2020
Hare SS, Rodrigues JCL, Jacob J, Edey A, Devaraj A, Johnstone A, McStay R, Nair A, Robinson G.   +8 more
europepmc   +1 more source