Results 141 to 150 of about 3,292,616 (334)

Subquery allocations in distributed databases using genetic algorithms

Journal of Computer Science and Technology, 2010
Minimization of query execution time is an important performance objective in distributed databases design. While total time is to be minimized for On Line Transaction Processing (OLTP) type queries, response time has to be minimized in Decision Support ...
Narasimhaiah Gorla, Suk-Kyu Song
doaj  

Reference database design for the automated analysis of microplastic samples based on Fourier transform infrared (FTIR) spectroscopy. [PDF]

Anal Bioanal Chem, 2018
Primpke S, Wirth M, Lorenz C, Gerdts G.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The PRO-ACT database: design, initial analyses, and predictive features. [PDF]

Neurology, 2014
Atassi N, Berry J, Shui A, Zach N, Sherman A, Sinani E, Walker J, Katsovskiy I, Schoenfeld D, Cudkowicz M, Leitner M.   +10 more
europepmc   +1 more source

The Brazilian Compound Library (BraCoLi) Database: A Brazilian Repository of Chemical and Biological Information for Drug Design [PDF]

, 2021
Gabriel Corrêa Veríssimo, Valtair Severino dos Santos, Ingrid Ariela do Rosário de Almeida, Marina Sant’Anna Mitraud Ruas, Lukas Galuppo Coutinho, Renata Barbosa de Oliveira, Vinícius Gonçalves Maltarollo   +6 more
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

PathCase-SB architecture and database design. [PDF]

BMC Syst Biol, 2011
Cakmak A, Qi X, Coskun SA, Das M, Cheng E, Cicek AE, Lai N, Ozsoyoglu G, Ozsoyoglu ZM.   +8 more
europepmc   +1 more source

Earlinet database: new design and new products for a wider use of aerosol lidar data [PDF]

, 2018
Lucia Mona, Giuseppe D’Amico, Francesco Amato, Holger Linnè, Holger Baars, Ulla Wandinger, Gelsomina Pappalardo   +6 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Design patterns of database models as storage systems for experimental information in solving research problems

, 2017
Denis E. Yablokov
openalex   +1 more source