Results 141 to 150 of about 16,804,247 (357)
A formal approach to the definition and the design of conceptual schemata for databased systems [PDF]
, 1982 Carlo Zaniolo, Michel A. Melkaoff
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Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
THE OBJECTUAL DATABASE DESIGN FOR A VIRTUAL STORE [PDF]
Annals of the University of Oradea: Economic Science, 2010 Nowadays, the most systems on the Internet are using databases. These databases are relational and normalized. Although the tables of the relational model itself does not have a behaviour in context object, though the diagrams uses different methods.
Avornicului Constantin +2 more
doaj
Issues in the design of database programming languages [PDF]
, 1980 Lawrence A. Rowe
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Derived classes as a basis for views in UML/OCL data models [PDF]
UML is the de facto standard language for analysis and design in object-oriented frameworks. Information systems, and in particular information systems based on databases and their applications, rely heavily on sound principles of analysis and design ...
Balsters, H.
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A database design methodology for an integrated database environment [PDF]
, 1983 Marian A. Herman
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Case study: the analysis, design & implementation of a database conversion [PDF]
, 1988 Vivie G. Babb
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