Results 161 to 170 of about 3,236,092 (351)

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

A design tool for object oriented databases [PDF]

open access: bronze, 1990
Mokrane Bouzeghoub   +3 more
openalex   +1 more source

NeurDB: On the Design and Implementation of an AI-powered Autonomous Database [PDF]

open access: yesCIDR 2025
Databases are increasingly embracing AI to provide autonomous system optimization and intelligent in-database analytics, aiming to relieve end-user burdens across various industry sectors. Nonetheless, most existing approaches fail to account for the dynamic nature of databases, which renders them ineffective for real-world applications characterized ...
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Building Scalable AI-Powered Applications with Cloud Databases: Architectures, Best Practices and Performance Considerations [PDF]

open access: yesarXiv
The rapid adoption of AI-powered applications demands high-performance, scalable, and efficient cloud database solutions, as traditional architectures often struggle with AI-driven workloads requiring real-time data access, vector search, and low-latency queries. This paper explores how cloud-native databases enable AI-driven applications by leveraging
arxiv  

Automated rapidplan model validation using Eclipse scripting API

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract RapidPlan offers efficiency gains and quality improvements in treatment planning. Prior to its use in the clinic, it requires an extensive validation procedure in which established clinical plans and those generated by the model are compared. The manual iterative nature of this process is resource intensive, as numerous iterations are required
Bradley Beeksma   +2 more
wiley   +1 more source

GEOGRAPHICAL INFORMATION SYSTEMS AND THE DURABLE CONSTRUCTION OF URBAN AND RURAL ENVIRONMENTS [PDF]

open access: yes
The idea of basis is the present condition and developing trend of cadastral management Valcea. The paper expatiates on the construction status of the Cadastral Management Information System on Integration of Urban and Rural area of Valcea.
Carmen RADUT
core  

Database Systems Course: Service Learning Project [PDF]

open access: yesarXiv
This paper describes a service learning project used in an upper-level and graduate-level database systems course. Students complete a small database project for a real client. The final product must match the client specification and needs, and include the database design and the final working database system with embedded user documentation.
arxiv  

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao   +34 more
wiley   +1 more source

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