Results 41 to 50 of about 17,028,074 (314)
The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
Frontiers in Immunology, 2017 The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics analytic tools and access to depositories of curated data relevant to immune reactions and specific pathogens.
Ward Fleri +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
H2O: An Autonomic, Resource-Aware Distributed Database System [PDF]
, 2010 This paper presents the design of an autonomic, resource-aware distributed database which enables data to be backed up and shared without complex manual administration.
Dearle, Alan +2 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Analysis of functionality free CASE-tools databases design
Открытое образование (Москва), 2016 The introduction in the educational process of database design CASEtechnologies requires the institution of significant costs for the purchase of software. A possible solution could be the use of free software peers.
A. V. Gavrilov
doaj +1 more source
Application domain ontology-based transformation to database design
Lietuvos Matematikos Rinkinys, 2021 The paper analyses graph oriented ontology transformation into conceptual data model. A number of methodswere proposed to develop conceptual datamodels, but only fewdealswith knowledge reuse.
Justas Trinkūnas, Olegas Vasilecas
doaj +1 more source
Relational Logic Database Design Model of Information System Control Project in Pt.istaka Karya [PDF]
, 1990 Analyzing this data is to provide a clearer picture about the functions of the dataelement or attribute is being investigated. After it was done depiction of therelationship (relationship) of an existing entity such entities.
Djoko Harmantyo, DR., M.Sc Djoko Harmantyo, DR., M.Sc +1 more
core
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
Nucleic Acids Res., 2016 The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins ...
Baofeng Jia +22 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source