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Analysis of functionality free CASE-tools databases design

open access: yesОткрытое образование (Москва), 2016
The introduction in the educational process of database design CASEtechnologies requires the institution of significant costs for the purchase of software. A possible solution could be the use of free software peers.
A. V. Gavrilov
doaj   +1 more source

Using Links to prototype a Database Wiki [PDF]

open access: yes, 2011
Both relational databases and wikis have strengths that make them attractive for use in collaborative applications. In the last decade, database-backed Web applications have been used extensively to develop valuable shared biological references called ...
Cheney, James   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Application domain ontology-based transformation to database design

open access: yesLietuvos Matematikos Rinkinys, 2021
The paper analyses graph oriented ontology transformation into conceptual data model. A number of methodswere proposed to develop conceptual datamodels, but only fewdealswith knowledge reuse.
Justas Trinkūnas, Olegas Vasilecas
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

District Energy Systems: Challenges and New Tools for Planning and Evaluation

open access: yesEnergies, 2020
The change from a centralized to a decentralized energy supply creates new challenges in the planning of such energy supply concepts. Specialized planning tools that can cope with the complex requirements and multi-layered boundary conditions of local ...
Steffen Wehkamp   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

HBIM for Conservation: A New Proposal for Information Modeling

open access: yesRemote Sensing, 2019
Thanks to its capability of archiving and organizing all the information about a building, HBIM (Historical Building Information Modeling) is considered a promising resource for planned conservation of historical assets.
Nazarena Bruno, Riccardo Roncella
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Evaluating ERD Models and RAID-Based Storage for Query Performance Optimization in Relational Databases

open access: yesJournal of Innovation Information Technology and Application
The amount of data stored in magnetic disks (e.g., floppy disks) increases by 100% each year for each department in a company, necessitating efforts to maintain an optimal database system.
Juanda Hakim Lubis   +3 more
doaj   +1 more source

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