Results 41 to 50 of about 1,281,790 (260)
Analysis of functionality free CASE-tools databases design
Открытое образование (Москва), 2016 The introduction in the educational process of database design CASEtechnologies requires the institution of significant costs for the purchase of software. A possible solution could be the use of free software peers.
A. V. Gavrilov
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
HBIM for Conservation: A New Proposal for Information Modeling
Remote Sensing, 2019 Thanks to its capability of archiving and organizing all the information about a building, HBIM (Historical Building Information Modeling) is considered a promising resource for planned conservation of historical assets.
Nazarena Bruno, Riccardo Roncella
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District Energy Systems: Challenges and New Tools for Planning and Evaluation
Energies, 2020 The change from a centralized to a decentralized energy supply creates new challenges in the planning of such energy supply concepts. Specialized planning tools that can cope with the complex requirements and multi-layered boundary conditions of local ...
Steffen Wehkamp +4 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Deriving Triggers from Integrity Constraint Specifications in the Database Management Systems
Acta Polytechnica, 2001 Supporting integrity constraints is essential for database systems. Integrity constraints are used to ensure that the data in a database complies with rules that have been set to establish accurate and acceptable information for a database.
M. Badawy, K. Richta
doaj
Optimization of Big Data Scheduling in Social Networks
Entropy, 2019 In social network big data scheduling, it is easy for target data to conflict in the same data node. Of the different kinds of entropy measures, this paper focuses on the optimization of target entropy.
Weina Fu, Shuai Liu, Gautam Srivastava
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FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source