Results 51 to 60 of about 1,755,080 (282)

Technical feasibility of a software project for virtualization of tasks performed by students in the higher education course - problems and solutions in evolutionary development [PDF]

open access: yesИкономика и компютърни науки, 2019
The dynamics of business requirements necessitates the modernization of teaching methods in schools and universities. The purpose of the publication is to explore the technological aspects of creating and maintaining a complex software system for virtual
Ivan Kuyumdzhiev
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A Database-Centric Framework for the Modeling, Simulation, and Control of Cyber-Physical Systems in the Factory of the Future

open access: yesJournal of Intelligent Systems, 2018
The factory of the future scenario asks for new approaches to cope with the incoming challenges and complexity of cyber-physical systems. The role of database management systems is becoming central for control and automation technology in this new ...
Bonci Andrea   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Event Indexing Systems for Efficient Selection and Analysis of HERA Data

open access: yes, 2001
The design and implementation of two software systems introduced to improve the efficiency of offline analysis of event data taken with the ZEUS Detector at the HERA electron-proton collider at DESY are presented.
Bauerdick, L. A. T.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Semi-automatic Database Design for Neuroscience Experiment Management Systems [PDF]

open access: yes, 2004
Neuroinformatics provides tools for neuroscience researchers to study brain function. In order to handle experiment paradigms that change frequently, we are developing a semiautomatic database design tool that will enable an experiment management system (
Brinkley, James F   +2 more
core   +1 more source

Anatomy of a Native XML Base Management System [PDF]

open access: yes, 2002
Several alternatives to manage large XML document collections exist, ranging from file systems over relational or other database systems to specifically tailored XML repositories.
Fiebig, Thorsten   +6 more
core   +3 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

An exploratory study on the emergence of management control systems: formalizing human resources in small growing firms [PDF]

open access: yes, 2005
The adoption of management control systems (MCS) is a key element in managing the tension that growth imposes on young growing firms. Despite its importance to a large number of organizations, only recently has the empirical literature devoted ...
Davila, Tony
core  

Home - About - Disclaimer - Privacy