Results 121 to 130 of about 27,273,409 (393)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
THE OBJECTUAL DATABASE DESIGN FOR A VIRTUAL STORE [PDF]
Annals of the University of Oradea: Economic Science, 2010 Nowadays, the most systems on the Internet are using databases. These databases are relational and normalized. Although the tables of the relational model itself does not have a behaviour in context object, though the diagrams uses different methods.
Avornicului Constantin +2 more
doaj
A Graphical Language-Based Approach for Database Modeling in Higher Education Information Systems
, 2023 Svitlana Kryshtanovych +4 more
openalex +2 more sources
, 2017 Sensors are present in various forms all around the world such as mobile phones, surveillance cameras, smart televisions, intelligent refrigerators and blood pressure monitors.
Küçükkeçeci, Cihan, Yazıcı, Adnan
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Model B4 : multi-decade creep and shrinkage prediction of traditional and modern concretes [PDF]
, 2014 To improve the sustainability of concrete infrastructure, engineers face the challenge of incorporating new concrete materials while pushing the expected design life beyond 100 years.
Bazant, Z. P. +2 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
A knowledge base architecture for distributed knowledge agents [PDF]
A tuple space based object oriented model for knowledge base representation and interpretation is presented. An architecture for managing distributed knowledge agents is then implemented within the model.
Riedesel, Joel, Walls, Bryan
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Modern thermodynamic databases: storing model parameters and model code in one place [PDF]
, 2022 Johannes Meeussen
openalex +1 more source