Results 221 to 230 of about 27,273,409 (393)

ePerturbDB: enhancer's experimental perturbation database. [PDF]

open access: yesDatabase (Oxford)
Maurya S, Sharma J, Mandoli A, Kumar V.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

A systematic polar-induced signature in infrasound database highlithed by machine learning models

open access: gold, 2023
Sentia Goursaud   +2 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

DL-RMD: A geophysically constrained electromagnetic resistivity model database for deep learning applications (Dataset)

open access: green, 2022
Muhammad Rizwan Asif   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A context-augmented large language model for accurate precision oncology medicine recommendations. [PDF]

open access: yesCancer Cell
Jun H   +19 more
europepmc   +1 more source

Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource

open access: yesNucleic Acids Res., 2004
M. Harris   +94 more
semanticscholar   +1 more source

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