Results 71 to 80 of about 26,204,206 (342)

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database

open access: yesNucleic Acids Res., 2017
The PharmMapper online tool is a web server for potential drug target identification by reversed pharmacophore matching the query compound against an in-house pharmacophore model database.
Xia Wang   +8 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

The BioGRID interaction database: 2017 update

open access: yesNucleic Acids Res., 2016
The Biological General Repository for Interaction Datasets (BioGRID: https://thebiogrid.org) is an open access database dedicated to the annotation and archival of protein, genetic and chemical interactions for all major model organism species and humans.
A. Chatr-aryamontri   +13 more
semanticscholar   +1 more source

XenDB: Full length cDNA prediction and cross species mapping in Xenopus laevis [PDF]

open access: yes, 2005
BACKGROUND: Research using the model system Xenopus laevis has provided critical insights into the mechanisms of early vertebrate development and cell biology.
Altmann, Curtis R   +4 more
core   +5 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

DB-GPT: Large Language Model Meets Database

open access: yesData Science and Engineering
Large language models (LLMs) have shown superior performance in various areas. And LLMs have the potential to revolutionize data management by serving as the "brain" of next-generation database systems.
Xuanhe Zhou, Zhaoyan Sun, Guoliang Li
doaj   +1 more source

Mouse Genome Database (MGD) 2019

open access: yesNucleic Acids Res., 2018
The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the community model organism genetic and genome resource for the laboratory mouse.
C. Bult   +5 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Integrated interactions database: tissue-specific view of the human and model organism interactomes

open access: yesNucleic Acids Res., 2015
IID (Integrated Interactions Database) is the first database providing tissue-specific protein–protein interactions (PPIs) for model organisms and human. IID covers six species (S. cerevisiae (yeast), C. elegans (worm), D.
M. Kotlyar   +3 more
semanticscholar   +1 more source

MEMBANDINGKAN MODEL-MODEL PENGEMBANGAN DATABASE [PDF]

open access: yes, 2008
Pengembangan Database didalam sistem informasi biasanya dimulai dengan enterprise data modeling yang umumnya digunakan untuk menentukan lingkup dan isi umum dari database yang dimaksud.
Hendra, Dwi Nofri   +4 more
core  

Home - About - Disclaimer - Privacy