Results 31 to 40 of about 124,288 (293)
A Novel Automatic Relational Database Normalization Method
Acta Informatica Pragensia, 2022 The increase in data diversity and the fact that database design is a difficult process make it practically impossible to design a unique database schema for all datasets encountered.
Emre Akadal, Mehmet Hakan Satman
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Automated Algorithm for Data Migration from Relational to NoSQL Databases
مجلة النهرين للعلوم الهندسية, 2018 One of the barriers that the developer community face once turning to the newly, highly distributable, schema agnostic and non-relational database, called NoSQL, which is how to migrate their legacy relational database (which is already filled with a ...
Alza A. Mahmood
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A Column Styled Composable Schema Matcher for Semantic Data-Types
Data Science Journal, 2019 Schema matching exists as a long-standing challenge in many database related applications, such as data integration, where two databases with different schema have to be integrated.
Xiaofeng Liao +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A Database Schema for Standardized Data and Metadata Collection in Agricultural Experiments
LandIn large-scale, multi-national research projects on agricultural cropping systems such as SoilCare (Horizon 2020), ensuring consistency, comparability, and timely reporting of the (meta)data of the agricultural experiments across diverse partners has ...
Ioanna S. Panagea +4 more
doaj +1 more source
Material Database Syndication with RSS
Data Science Journal, 2007 Every material database on the Internet has a different data schema. There are some trial attempts to define unified schema for material databases, but since the structure of scientific data is very complicated and changes dynamically, defining a ...
Toshihiro Ashino, Nobuto Oka
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source