Results 61 to 70 of about 124,288 (293)
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
A multi-layer Internet of things database schema for online-to-offline systems
Due to the widespread usage of Internet of things devices in online-to-offline businesses, a huge volume of data from heterogeneous data sources are collected and transferred to the data processing components in online-to-offline systems.
Hongming Cai +6 more
doaj +1 more source
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake +12 more
wiley +1 more source
Schema Management for Data Integration: A Short Survey
Schema management is a basic problem in many database application domains such as data integration systems. Users need to access and manipulate data from several databases.
A. Almarimi, J. Pokorný
doaj
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel +3 more
wiley +1 more source
Schema Vacuuming in Temporal Databases [PDF]
Temporal databases facilitate the support of historical information by providing functions for indicating the intervals during which a tuple was applicable (along one or more temporal dimensions). Because data are never deleted, only superceded, temporal databases are inherently append-only resulting, over time, in a large historical sequence of ...
openaire +2 more sources
This study examines how several molten high‐silicon electrical steels interact with both conventional and recycled MgO–C refractories. For this, various immersion experiments are conducted. In addition to infiltration, a number of mechanisms are identified and explained that control the corrosion of the refractory material.
Lukas Neubert +7 more
wiley +1 more source
IGSQL: Database Schema Interaction Graph Based Neural Model for Context-Dependent Text-to-SQL Generation [PDF]
Yitao Cai, Xiaojun Wan
openalex +3 more sources

