Results 151 to 160 of about 2,577,242 (312)

Elderly Liver Grafts are More Susceptible to Ischemia‐Reperfusion After Prolonged Cold Ischemia than Grafts from Young Donors—An Ex Vivo Liver Machine Perfusion Analysis in Sprague Dawley Rats

open access: yesAdvanced Therapeutics, EarlyView.
This study investigates how donor age and cold ischemia time influence liver perfusion parameters and injury markers. Older livers are more susceptible to longer ischemia times displaying more tissue damage, and higher expression of oxidative stress and apoptosis‐related proteins than livers with shorter ischemia times.
Leonard Boerger   +12 more
wiley   +1 more source

TVB C++: A Fast and Flexible Back‐End for The Virtual Brain

open access: yesAdvanced Science, EarlyView.
TVB C++ is a streamlined and fast C++ Back‐End for The Virtual Brain (TVB), designed to make it as flexible as TVB, and FAST. Another pillar is to be fully compatible with TVB so easy bindings can be created from Python. Users can easily configure TVB C++ to execute the same code but with enhanced performance and parallelism.
Ignacio Martín   +7 more
wiley   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan   +20 more
wiley   +1 more source

SAP HANA distributed in-memory database system: Transaction, session, and metadata management

open access: yesIEEE International Conference on Data Engineering, 2013
Juchang Lee   +8 more
semanticscholar   +1 more source

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

open access: yesAdvanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh   +11 more
wiley   +1 more source

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