Results 51 to 60 of about 2,504,885 (377)
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
A new secure 2PL real-time concurrency control algorithm (ES2PL)
A secure concurrency control algorithms must be devoid of covert channels originating from data conflicts between transactions, in addition to ensuring database integrity.
Ebrahim Abduljalil+4 more
doaj
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Blockchain: An Overview and Its Applications in Aviation
Blockchain is a type of distributed database managed through multiple network transaction details (P2P, Peer to Peer), and transaction information is stored on multiple computers (nodes) connected to the blockchain network instead of storing it in one
WooSeok Hyun
doaj +1 more source
Health-care databases and its role in transformation of medicine
Health-care database is a collection of health-care data organized for storage, accessibility, and retrieval. Health-care database serves to replace the paper documents, filing cabinets of old, and file folders, which will be more convenient and ...
Lakshmi Venkata Simhachalam Kutikuppala+4 more
doaj +1 more source
Process as a world transaction [PDF]
Transaction is process closure: for a transaction is the limiting process of process itself. In the process world view the universe is the ultimate (intensional) transaction of all its extensional limiting processes that we call reality.
Heather, Michael+2 more
core
Schema architecture and their relationships to transaction processing in distributed database systems [PDF]
We discuss the different types of schema architectures which could be supported by distributed database systems, making a clear distinction between logical, physical, and federated distribution. We elaborate on the additional mapping information required
Apers, P.M.G., Scheuermann, P.
core +2 more sources
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
State of the art and future research on distributed processing system in Internet environment
Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj