Results 241 to 250 of about 5,268,956 (336)

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Genetic epidemiology of moyamoya disease and CADASIL in over 120,000 healthy Korean individuals: Insights into cerebrovascular disorders. [PDF]

PLoS One
Cho EH, Lee M, Ki CS, Seol CA, Jang MA.
europepmc   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

One-Sided Matching Portal (OSMP): A Tool to Facilitate Rare Disease Patient Matchmaking. [PDF]

Hum Mutat
Osmond M, Price EM, Buske OJ, Frew M, Couse M, Hartley T, Klamann C, Le HGBH, Xu J, So D, Jain A, Lu K, Mo K, Wyllie H, Wall E, Driver HG, Cheung WA, Cohen ASA, Farrow EG, Thiffault I, Consortium CRC, Turinsky AL, Pastinen T, Brudno M, Boycott KM.   +24 more
europepmc   +1 more source

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen, Henrik Horwitz, Ida M. Heerfordt, Elisabeth Framke, Melinda Magyari   +4 more
wiley   +1 more source

C15ORF48 serves as a potential biomarker and therapeutic target in pan-cancer with implications for lung cancer. [PDF]

Sci Rep
Ren J, Zhu H, Liu M, Zhang R, Mao W, Xiao S.   +5 more
europepmc   +1 more source

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

Nature Biotechnology, 2014
H. B. Nielsen, Mathieu Almeida, A. S. Juncker, Simon Rasmussen, Junhua Li, S. Sunagawa, D. Plichta, Laurent Gautier, Anders G Pedersen, E. Le Chatelier, Eric Pelletier, Ida Bonde, Trine Nielsen, C. Manichanh, Manimozhiyan Arumugam, Jean-Michel Batto, Marcelo B Quintanilha dos Santos, Nikolaj S. Blom, N. Borruel, K. Burgdorf, F. Boumezbeur, Francesc Casellas, J. Doré, Piotr Dworzynski, F. Guarner, T. Hansen, F. Hildebrand, R. Kaas, Sean Kennedy, Karsten Kristiansen, Jens Roat Kultima, Pierre Leonard, F. Levenez, Ole Lund, Bouziane Moumen, Denis Le Paslier, N. Pons, Oluf Pedersen, Edi Prifti, Junjie Qin, Jeroen Raes, Søren J Sørensen, Julien Tap, S. Tims, D. Ussery, Takuji Yamada, H Bjørn Mathieu Agnieszka S Simon Junhua Shinichi Da Nielsen Almeida Juncker Rasmussen Li Sunagawa Plic, A. S. Juncker, Manimozhiyan Arumugam, Karsten Kristiansen, Pierre Leonard, P. Renault, Thomas Sicheritz-Pontén, P. Bork, Jun Wang, S. Brunak, S. Ehrlich, A. Jamet, Alexandre Mérieux, Antonella Cultrone, A. Torrejon, B. Quinquis, Christian Bréchot, C. Delorme, Christine M'Rini, Willem M. de Vos, Emmanuelle Maguin, E. Varela, É. Guédon, Falony Gwen, Florence Haimet, F. Artiguenave, Gaetana Vandemeulebrouck, G. Denariaz, Ghalia Khaci, H. Blottière, Jan Knol, Jean Weissenbach, J. V. H. van Hylckama Vlieg, J. Torben, Julian Parkhill, K. Turner, M. van de Guchte, M. Antolín, Maria Rescigno, M. Kleerebezem, M. Derrien, N. Galleron, Nicolas Sanchez, N. Grarup, P. Veiga, R. Oozeer, R. Dervyn, Séverine Layec, T. Bruls, Yohanan Winogradski, Zoetendal Erwin G, S. Brunak, S. Ehrlich   +98 more
semanticscholar   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

18 individual genes underwent variant screening in a northwest Chinese group comprised 83 probands diagnosed with early-onset high myopia. [PDF]

PLoS One
Liu Y, Zhang SC, Zhang W, Xue ZQ, Qin YX, Piao SY, Li WJ, Ji ML, Zhuang WJ.   +8 more
europepmc   +1 more source