A case for glycerol as an acceptable additive for single‐particle cryoEM samples
It is shown that the inclusion of glycerol in single‐particle cryoEM buffers does not preclude high‐resolution structure determination, as demonstrated by an ∼2.3 Å resolution reconstruction of mouse apoferritin (∼500 kDa) and an ∼3.3 Å resolution reconstruction of rabbit muscle aldolase (∼160 kDa) in the presence of 20%(v/v) glycerol.Buffer ...
Benjamin Basanta+3 more
wiley +1 more source
Recent developments in the Phenix software package are described in the context of macromolecular structure determination using X‐rays, neutrons and electrons.Diffraction (X‐ray, neutron and electron) and electron cryo‐microscopy are powerful methods to determine three‐dimensional macromolecular structures, which are required to understand biological ...
Dorothee Liebschner+24 more
wiley +1 more source
Relationships between childhood trauma and multiple sclerosis: A systematic review. [PDF]
Polick CS, Polick SR, Stoddard SA.
europepmc +1 more source
Active label cleaning for improved dataset quality under resource constraints. [PDF]
Bernhardt M+11 more
europepmc +1 more source
Surveillance of COVID-19 Vaccination in Nursing Homes, United States, December 2020-July 2021. [PDF]
Geller AI+10 more
europepmc +1 more source
The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline. [PDF]
Apprato G, Ermondi G, Caron G.
europepmc +1 more source
Has COVID-19 Affected Cancer Screening Programs? A Systematic Review. [PDF]
Alkatout I+6 more
europepmc +1 more source
Shelter from the storm: Acetaminophen (paracetamol) in pregnancy, urogenital malformations, and childhood neurodevelopment. [PDF]
Damkier P, Hodson K.
europepmc +1 more source
AI for Population and Global Health in Radiology. [PDF]
Anazodo UC, Adewole M, Dako F.
europepmc +1 more source
Examining the characteristics of social and behavior change communication intervention costs in low- and middle-income countries: A hedonic method approach. [PDF]
Bollinger LA, Bellows N, Linder R.
europepmc +1 more source