Results 111 to 120 of about 4,971,844 (261)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Exploring the Impact of Dataset Bias on Dataset Distillation

2024 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)
Dataset Distillation (DD) is a promising technique to synthesize a smaller dataset that preserves essential information from the original dataset. This synthetic dataset can serve as a substitute for the original large-scale one, and help alleviate the training workload.
Yao Lu 0041, Jianyang Gu, Xuguang Chen, Saeed Vahidian, Qi Xuan 0001   +4 more
openaire   +2 more sources

Satellite-Based Forest Stand Detection Using Artificial Intelligence

IEEE Access
The forest constitutes an essential and irreplaceable component of life for all organisms, with its primary significance lying in its role in creating a breathable atmosphere on Earth.
Patrik Kovacovic, Rastislav Pirnik, Julia Kafkova, Mario Michalik, Alzbeta Kanalikova, Pavol Kuchar   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

DaRA Dataset: Combining Wearable Sensors, Location Tracking, and Process Knowledge for Enhanced Human Activity and Human Context Recognition in Warehousing

Sensors
Understanding human movement in industrial environments requires more than simple step counts—it demands contextual information to interpret activities and enhance workflows. Key factors such as location and process context are essential.
Friedrich Niemann, Fernando Moya Rueda, Moh’d Khier Al Kfari, Nilah Ravi Nair, Dustin Schauten, Veronika Kretschmer, Stefan Lüdtke, Alice Kirchheim   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

DSC: depth data quality optimization framework for RGBD camouflaged object detection

Open Physics
Camouflaged object detection (COD) faces unique challenges due to the extremely high visual similarity between objects and their surroundings, coupled with indistinct boundary features.
Zhang Dongdong, Wang Chunping, Fu Qiang, Cheng Yue, Li Zhaorui, Yang Qing   +5 more
doaj   +1 more source

HHCS: A Dataset of Cipher Symbol Annotations From Handwritten Historical Encrypted Documents for Machine Learning Tasks

IEEE Access
Many historical documents, including military and diplomatic correspondence, were encrypted to protect sensitive information. The study of historical cryptology remains an important research area, as deciphering these sources can reveal new historical ...
Eugen Antal, Pavol Marak, Filip Mikus
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Data Acquisition for Detecting Low-observable Targets at Sea by Using the Holographic Staring Radar

Leida xuebao
Detecting targets despite sea clutter is crucial in military and civilian applications. In complex marine environments, sea clutter exhibits target-like spikes and inherently broad-spectrum characteristics, posing a significant challenge for marine ...
Qi SU, Benyuan LIU, Xiaotian CHEN, Guangxin ZHI, Lingyun YE   +4 more
doaj   +1 more source