Results 61 to 70 of about 5,362,697 (261)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

KMSAV: Korean multi-speaker spontaneous audiovisual dataset

ETRI Journal
Recent advances in deep learning for speech and visual recognition have accelerated the development of multimodal speech recognition, yielding many innovative results. We introduce a Korean audiovisual speech recognition corpus.
Kiyoung Park, Changhan Oh, Sunghee Dong
doaj   +1 more source

Learning Frame-Level Classifiers for Video-Based Real-Time Assessment of Stroke Rehabilitation Exercises From Weakly Annotated Datasets

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Autonomous rehabilitation support solutions, such as virtual coaches, should provide real-time feedback to improve motor function and maintain patient engagement.
Ana Rita Coias, Min Hun Lee, Alexandre Bernardino, Asim Smailagic, Mariana Mateus, David Fernandes, Sofia Trapola   +6 more
doaj   +1 more source

A set of time‐series classification datasets based on the average price of concrete in major Chinese cities

Engineering Reports, 2022
Time series classification (TSC) is an important and challenging problem in data mining. Time series data sets are an important basis for this research and are widely used in baseline verification of various algorithm models.
Qing Liu, Minghao Huang, Woon‐Seek Lee, Yamin Du   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

THE ISSUE OF TRAINING OF THE NEURAL NETWORK FOR DRONE DETECTION

Сучасні інформаційні системи
In the article, the issue of mistaking birds for UAVs, which is considered one of the main problems in the process of detecting unmanned aerial vehicles (UAVs) through cameras, was considered.
Elshan Hashimov , Giblali Khaligov
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Deep-learning based model for sperm morphology assessment using the SMD/MSS dataset

Future Science OA
Background Manual sperm morphology assessment is recognized as a challenging parameter to standardize due to its subjective nature, often reliant on the operator’s expertise. Our study aims to address this issue by developing a predictive model for sperm
Olfa Abdelkefi, Rania Maalej, Tarek Rebai, Afifa Sellami, Salima Daoud   +4 more
doaj   +1 more source

Help me describe my data: A demonstration of the Open PHACTS VoID Editor [PDF]

, 2014
. The Open PHACTS VoID Editor helps non-Semantic Web experts to create machine interpretable descriptions for their datasets. The web app guides the user, an expert in the domain of the data, through a series of questions to capture details of their ...
Goble, Carole, Gray, Alasdair J G, Tatakis, Eleftherios   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source