We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
Epidemiological and digital syndromic surveillance data on dengue, chikungunya, and SARI in Brazil. [PDF]
Borges ME +3 more
europepmc +1 more source
A Termite‐Inspired Alternative to Cement
A termite‐inspired composite of clay, cellulose, and lignin forms a dense fibrous network with concrete‐like strength (32 MPa) and superior elasticity, processed at ambient temperature. Abstract Clay combined with organic materials is used by termites as a strong and durable construction material for their mounds with minimal environmental impact. Here,
Oren Regev +3 more
wiley +1 more source
Topic analysis on publications and patents toward fully automated translational science benefits model impact extraction. [PDF]
Manjunath T +5 more
europepmc +1 more source
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng +9 more
wiley +1 more source
A machine learning based empathy mapping framework for enhancing user experience through app review analysis. [PDF]
Ishfaq F +5 more
europepmc +1 more source
Editorial: Theoretical advances and practical applications of spiking neural networks, volume II. [PDF]
Di Caterina G, Zhang M, Liu J.
europepmc +1 more source
Editorial: Innovation in tackling the global challenge of eradicating antibiotic-resistant microorganisms. [PDF]
Nissan I, Peretz A.
europepmc +1 more source
A computational framework to dissect imputation strategies for single-cell histone modification data. [PDF]
Moreno-González M +3 more
europepmc +1 more source
SpaTM: topic models for inferring spatially informed transcriptional programs. [PDF]
Osakwe A +4 more
europepmc +1 more source

