Results 181 to 190 of about 208,010 (304)

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Psychometric Properties of Instruments for Perpetration and Victimization of Dating Violence in Young People: Systematic Review and Meta-Analysis. [PDF]

Eur J Investig Health Psychol Educ
Ramírez A, Burgos-Benavides L, Sinchi-Sinchi H, Herrero Díez J, Rodríguez-Díaz FJ.   +4 more
europepmc   +1 more source

Three-Year Outcomes From a Middle School Dating Violence Prevention Program. [PDF]

Pediatrics, 2023
Baumler E, Wood L, Temple JR.
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Cross-Sectional and Longitudinal Associations Between Pornography Use and Dating Violence Victimization: Are There Risks for Teenagers? [PDF]

J Interpers Violence
Martel S, Bergeron S, Bőthe B, Vaillancourt-Morel MP, Hébert M, Dion J.   +5 more
europepmc   +1 more source

Dating violence [Reportaje]

, 2016
La violencia de género afecta a muchos jóvenes. Desde que hace unos años en 2012, el juzgado de menores comenzó a ofrecer datos sobre esta lacra social, el número de jóvenes enjuiciados por casos de violencia de género ha crecido considerablemente de los 114 de 2012 a un total de 162 jóvenes en 2015.
openaire   +2 more sources

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Psychosocial determinants of adolescents' attitudes toward disclosing dating violence. [PDF]

Am J Orthopsychiatry
Sianko N, Kunkel D, Burke SR, Duncan S, Small MA.   +4 more
europepmc   +1 more source

Measurement of Adolescent Dating Violence in Sexual Minority Youth: A Scoping Review. [PDF]

Aggress Violent Behav, 2023
Ricks JM, Montgomery CM, Nash JA.
europepmc   +1 more source

Metabolic Regulation of Dimethylsulfoniopropionate Cleavage and Dimethyl Sulfide Production in Halomonas sp. D47

Advanced Science, EarlyView.
Dimethylsulfoniopropionate (DMSP) is a major marine organosulfur compound central to climate‐relevant dimethyl sulfide (DMS) production. In Halomonas sp. D47, DMSP catabolism is revealed to be coordinated by two transcriptional regulators, AcuR and AcuZ, which control gene expression by sensing DMSP and its metabolites.
Li‐Yuan Zheng, Wen‐Xin Jiang, Xiao‐Meng Sun, Li Liu, Zhao‐Jie Teng, Hou‐Qi Wang, Wen‐Jing Zhu, Chang Ge, Qi‐Long Qin, Ning‐Hua Liu, Hai‐Yan Cao, Hui‐Hui Fu, Chun‐Yang Li, Jonathan D. Todd, Xiu‐Lan Chen, Yu‐Zhong Zhang, Peng Wang   +16 more
wiley   +1 more source