Results 281 to 290 of about 213,281 (348)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Effects of a Dating Violence Prevention Program for High School Students

open access: diamond
Junko Ueno   +4 more
openalex   +2 more sources

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

open access: yesAnnals of Neurology, EarlyView.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov   +42 more
wiley   +1 more source

Gender-Based Dating Violence and Social Media among Spanish Young People: A Qualitative Study. [PDF]

open access: yesBehav Sci (Basel)
García-Ruiz M   +4 more
europepmc   +1 more source

Teen dating violence: predictive role of sexism and the mediating role of empathy and assertiveness based on gender. [PDF]

open access: yesFront Psychol
Villanueva-Blasco VJ   +7 more
europepmc   +1 more source

Adaptation and feasibility assessment of a dating violence prevention program for girls in foster care. [PDF]

open access: yesPsicol Reflex Crit
de Moura JQ   +5 more
europepmc   +1 more source

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