Results 81 to 90 of about 213,281 (348)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Dating violence and nursing student well-being

open access: yesAtención Primaria, 2014
Background: Violence in dating relationships involves dimensions such as physical, psychological and sexual abuse, requiring strategies for prevention and early intervention.
Conceição Martins   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Dating violence and mental health issues in Ecuadorian university students

open access: yesFrontiers in Sociology
ObjectiveThe aim of this study was to analyze the relationship between dating violence and mental health issues in young university students in Ecuador examining differences between men and women.MethodsThis investigation used a quantitative, descriptive
Mayra Castillo-Gonzáles   +1 more
doaj   +1 more source

Defining Violence on the Blackboard: An Overview of the Texas Education Code's Approach to Teen Dating Violence (Comment) [PDF]

open access: yes, 2010
Texas has taken a pioneering step by creating § 37.0831 of the Texas Education Code (the Teen Dating Violence statute) requiring Texas school districts to implement a dating violence policy in their schools.
Jessica Ramos
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Exploring Family Functioning in Adolescent Dating Violence: A Case Study of an Indonesian Spiritual Community

open access: yesHealth Dynamics
Background: Adolescence is a period of transition from childhood to adulthood. One of the significant changes during this period is changes in behavior related to sexual life.
Putri Eka Sejati   +3 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Sexual Double Standard, Dating Violence Recognition, and Sexual Assertiveness among University Students in South Korea

open access: yesAsian Nursing Research, 2019
Purpose: This study aimed to examine the association among sexual double standard, dating violence recognition, and sexual assertiveness among Korean university students.
Yujeong Kim, Eunmi Lee, Haeyoung Lee
doaj   +1 more source

Kekerasan dalam Pacaran dan Kecemasan Remaja Putri di Kabupaten Purworejo [PDF]

open access: yes, 2012
Background: Gender-based violence in Indonesia is that many cases occur. Since 1998,violence in dating the Rifka Annisa Women's Crisis Center is a case of the second largest afterthe violence against wives.
Ayu, S. M. (Suci)   +2 more
core  

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