Results 211 to 220 of about 711,478 (286)

Acromegaly Presenting With Cricoarytenoid Joint Arthropathy

open access: yesThe Laryngoscope, EarlyView.
Excess growth hormone in acromegaly induces characteristic acral and soft tissue overgrowth (particularly in the face and hands), arthropathies, as well as cardiovascular and metabolic complications. Similar proliferative changes can occur in the larynx, where hypertrophy of the arytenoid and cricoid cartilages may impair vocal fold mobility.
Samantha Salvi Cruz   +3 more
wiley   +1 more source

Mechanophoric 3‐Arm Star Functional Block Copolymer Based on Rhodamine Derivative

open access: yesMacromolecular Materials and Engineering, EarlyView.
Mechanoresponsive rhodamine containing linear and star block and random copolymers were synthesized and characterized. All materials transitioned into a “switch‐on” state in the film form, but only the star block copolymer architecture exhibited a complete and precise peak shift upon stretching, providing new insights into the mechanochemical ...
Swadhin Chakraborty   +8 more
wiley   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri   +20 more
wiley   +1 more source

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p.A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis   +213 more
wiley   +1 more source

Intratumoral Bacteria: Accomplices in Cancer Progression and Emerging Therapeutic Targets

open access: yesMedicine Advances, EarlyView.
Intratumoral bacteria are no longer seen as contaminants but as active contributors to cancer progression, driving therapy resistance and metastasis through metabolic reprogramming, immunomodulation, and metastatic niche formation. This review highlights emerging microbiome‐targeted strategies—including synthetic microbial consortia, engineered ...
Jie Yang   +3 more
wiley   +1 more source

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