Results 31 to 40 of about 275,784 (309)

Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo

Neurobiology of Disease, 2020
Amyotrophic Lateral Sclerosis (ALS), a late-onset neurodegenerative disorder characterized by the loss of motor neurons in the central nervous system, has no known cure to-date.
Neha Gogia, Ankita Sarkar, Abijeet Singh Mehta, Ph.D., Nandini Ramesh, Prajakta Deshpande, Madhuri Kango-Singh, Udai Bhan Pandey, Amit Singh   +7 more
doaj   +1 more source

Photonic Time Crystals and Time‐Varying Electromagnetic Metamatter: A New Direction for Ultrafast Tunable Photonic and Microwave Materials and Devices

Advanced Science, EarlyView.
Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel, Shriram Ramanathan, Ronald P. Jenkins, Michael J. Carter   +3 more
wiley   +1 more source

Protocol to study cell death using TUNEL assay in Drosophila imaginal discs

STAR Protocols, 2022
Summary: Cell death maintains tissue homeostasis by eliminating dispensable cells. Misregulation of cell death is seen in diseases like cancer, neurodegeneration, etc.
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Abijeet Singh Mehta, Amit Singh   +3 more
doaj   +1 more source

Review of “The Church in a Postliberal Age,” by George Lindbeck [PDF]

, 2004
Dr. Lysaught reviews George Lindbeck\u27s book The Church in a Postliberal Age. M.
Lysaught, M. Therese
core   +1 more source

Diffusion Characteristics of Ru and Oxygen Vacancies in Ta2O5 for Resistive Random Access Memory Devices: A Density Functional Theory Investigation

Advanced Electronic Materials, EarlyView.
Atomistic analysis of ruthenium (Ru) and oxygen vacancy (OV) diffusion in Ta₂O₅‐based memristors is performed. DFT calculations demonstrate interstitial Ru in Ta₂O₅ has lower diffusion barriers and formation energies than OVs, enhancing mobility and stability.
Md. Sherajul Islam, Sabyasachi Ganguli, J. Joshua Yang, Ajit K Roy   +3 more
wiley   +1 more source

Letter Written by Patricia O\u27Brien Aiken to Lieutenant Albert Shelton Aiken dated February 13, 1943 [PDF]

, 1943
Well Baby – The day felt just like I did so it rained like hell. I hope you are having a terrible time in Dayton & are wishing to heaven you had me there after all.
Aiken, Patricia O\u27Brien
core   +9 more sources

A Call to Activism, review of \u3cem\u3eTheological Bioethics,\u3c/em\u3e by Lisa Cahill [PDF]

, 2007
Dr. Lysaught reviews Lisa Cahill\u27s book Theological Bioethics: Participation, Justice, and Change. M.
Lysaught, M. Therese
core   +1 more source

Differences in predominant collagen fiber orientation between dorsal and plantar trabecular bone tracts of adult mule deer calcanei suggest strain‐mode‐specific adaptation

The Anatomical Record, EarlyView.
Polarized microscopic images of the outer bone cortex (a and b) and deeper trabecular bone (c and d) of the deer calcaneus in thin cross‐sections. The brighter gray levels reflect more oblique‐to‐transverse collagen fibers in the compression/dorsal bone (a, c) and the darker gray levels reflect more longitudinal collagen in the tension/plantar bone (b,
John G. Skedros, John T. Cronin, Chad S. Mears, Brett W. Richards   +3 more
wiley   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Current understanding and distinct features of multifocal and multicentric breast cancers

Cancer Reports, 2023
Background Multifocal (MF) and multicentric (MC) breast cancers are referred to as synchronous, multiple ipsilateral breast cancers; however, the definitions vary among the literature, which has made understanding and analyzing these diseases challenging.
Elizabeth Avera, Lilia Valentic, Loan Bui   +2 more
doaj   +1 more source