Ultrafast Electron Dynamics of a Ferrocene-Based Butadiyne-Bridged Complex. [PDF]
Mendis KC +7 more
europepmc +1 more source
A Pd(0)‐catalyzed cyclotrimerization of benzoCOTynes to form tri(benzo[8]annulenes) was developed. Three distinct isomers were isolated and structurally characterized by single‐crystal X‐ray diffraction. Ligand modulation proved crucial for enhancing regioselectivity: P(4‐OMePh), and (S)‐tBu‐Phox promoted the formation of the symmetric isomers.
Jesús Bello‐García +2 more
wiley +1 more source
Calibration-free sEMG intention recognition via self-supervised pretraining and adversarial domain alignment for upper-limb rehabilitation. [PDF]
Yang Y +5 more
europepmc +1 more source
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč +8 more
wiley +1 more source
Video Head Impulse test findings in young adults with long-term use of Personal Listening Devices. [PDF]
Dessai TD, Sunny JM, Bhat RJ, Kumar K.
europepmc +1 more source
Optimisation of a Novel Class of DNA Gyrase Inhibitors to Improve Antibacterial Activity
This article describes efforts to increase the antibacterial activity of a recently reported class of novel DNA gyrase inhibitors known as the isoquinoline sulphonamides by improving their uptake in bacterial cells. As antibiotic resistance continues to rise, the need for new antibacterials is clear.
Meg I. Ferguson +9 more
wiley +1 more source
Myricetin Inhibits <i>Toxoplasma gondii</i> Growth, Alters Intracerebral Cyst Morphology, and Demonstrates Therapeutic Efficacy In Vivo. [PDF]
Ge CC +7 more
europepmc +1 more source
Probing 3‐Amino‐2H‐Azaindazoles as Allosteric Inhibitors of the Protein Tyrosine Phosphatase SHP2
A palladium‐catalyzed domino reaction facilitated the discovery and rapid synthesis of selective, potent 3‐amino‐2H‐azaindazole derivatives serving as allosteric inhibitors of SHP2. Structural analysis via co‐crystallography confirmed binding at the allosteric site, thereby stabilizing the autoinhibited SHP2 conformation, qualifying this scaffold as a ...
Machoud Amoussa +20 more
wiley +1 more source
Serotonin Associated Mechanisms in Sudden Unexpected Death in Epilepsy: A Review. [PDF]
Li B +6 more
europepmc +1 more source
A modular library of structurally robust palladacyclopentadienyl Pd(II) complexes bearing achiral and chiral diphosphines was developed, revealing a strong influence of diphosphine design and ligand chirality on cytotoxicity and selectivity against ovarian cancer cells, including platinum‐resistant models.
Stefania Mautone +7 more
wiley +1 more source

