Results 51 to 60 of about 41,032 (278)

Variation in the mechanical unfolding pathway of p53DBD induced by interaction with p53 N-terminal region or DNA. [PDF]

PLoS ONE, 2012
The tumor suppressor p53 plays a crucial role in the cell cycle checkpoints, DNA repair, and apoptosis. p53 consists of a natively unfolded N-terminal region (NTR), central DNA binding domain (DBD), C-terminal tetramerization domain, and regulatory ...
Yukinori Taniguchi, Masaru Kawakami
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

PERILAKU PENCEGAHAN TERHADAP KEJADIAN DEMAM BERDARAH DENGUE PADA MASYARAKAT

Jurnal Kesehatan Budi Luhur, 2021
Penyakit Demam Berdarah Dengue (DBD) merupakan salah satu masalah kesehatan masyarakat di Indonesia karena dapat menyerang seluruh kelompok umur dan sering menimbulkan kematian. Angka kesakitan di wilayah Kabupaten Cianjur pada tahun 2018 yaitu terdapat
Atira, Vera Legina Sukmarahayu, Rima Phytriyani   +2 more
doaj   +1 more source

The International Consortium for Arthrogryposis: A Collaborative Framework for Early Detection, Care, Research, and Education

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is a group of rare congenital conditions, characterized by multiple joint contractures but may involve any body system including central nervous system. AMC is etiologically heterogeneous, with over 400 genetic and many non‐genetic causes implicated in its prenatal development.
Shahrzad Nematollahi, Noa Bouzaglo, Victoria Castillo Sanchez, Johanna I. P. de‐Vries, Klaus Dieterich, Alicja Fafara, Isabel Filges, Philip Giampietro, Göknur Haliloğlu, Judith Hall, Coleman Hilton, Remco Jansen, Valentina Maestri, Carolina Navalon, Daniel Natera de Benito, Tony Pan, Ani Samargian, Bonita Sawatzky, Harold van Bosse, Paul A. Trainor, Noémi Dahan‐Oliel   +20 more
wiley   +1 more source

Probing the mechanism of recognition of ssDNA by the Cdc13-DBD [PDF]

Nucleic Acids Research, 2008
The Saccharomyces cerevisiae protein Cdc13 tightly and specifically binds the conserved G-rich single-stranded overhang at telomeres and plays an essential role in telomere end-protection and length regulation. The 200 residue DNA-binding domain of Cdc13 (Cdc13-DBD) binds an 11mer single-stranded representative of the yeast telomeric sequence [Tel11, d(
Eldridge, Aimee M., Wuttke, Deborah S.
openaire   +2 more sources

Waspadai DBD Demam Berdarah Dengue dan Chikungunya [PDF]

, 2010
vi, 89 ...
Sanjari, Anno D, Rasyid
core  

Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy

Animal Models and Experimental Medicine, EarlyView.
Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan, Khushbakhat Alia, Yusra Al Dhaheri, Muhammad Naseem, Rabah Iratni, Edgar Serfling, Khalid Muhammad   +6 more
wiley   +1 more source

Anticonstriction Effect of MCA in Rats by Danggui Buxue Decoction

Frontiers in Pharmacology, 2021
Objective: Danggui Buxue decoction (DBD), consisting of Angelicae Sinensis Radix (ASR) and Astragali Radix (AR), is a famous prescription with the function of antivasoconstriction.
Ying Guo, Ying Guo, Yating Zhang, Ya Hou, Pengmei Guo, Xiaobo Wang, Sanyin Zhang, Sanyin Zhang, Peng Yang   +8 more
doaj   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Ozone Plasma Nanobubble (OPN) Reactor Combined with Coagulation-Flocculation Process: A Promising Technology for Leachate Treatment

Indonesian Journal of Chemistry
According to World Bank data, approximately 2.01 billion tons of urban waste is produced annually, with approximately 33% of waste being improperly managed, leading to concentrated and toxic leachate.
Habiibatuz Zahra, Ken Azzahra, Azizka Inneke Putri, Veny Luvita, Setijo Bismo   +4 more
doaj   +1 more source