Results 91 to 100 of about 7,769,894 (338)

Carbon/graphite fiber risk analysis and assessment study: An assessment of the risk to Douglas commercial transport aircraft [PDF]

The potential hazard to electrical and electronic devices should there be a release of free carbon fibers due to an aircraft crash and fire was assessed. Exposure and equipment sensitivity data were compiled for a risk analysis.
Cook, C. Q., Gilles, D. L., Henning, B., Hosford, J., Schjelderup, H. C., Snyder, E., Swanstrom, C. W.   +6 more
core   +1 more source

Shot noise in superconducting junctions with weak link formed by Anderson impurity

, 2000
A theory is developed to study shot noise in superconducting (SAS) and hybrid (SAN) junctions with singly occupied Anderson impurity (A) as a weak link. The zero-frequency DC component of the shot noise spectral density is calculated at zero temperature ...
A Golub, A. D Zaikin, Hessling J. P., Hoss T., Khlus V. A., Khlus V. A., Naidenov S. V., Vystavkin A. N., Vystavkin A. N., Y Avishai   +9 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

DC Offset Error Compensation Algorithm for PR Current Control of a Single-Phase Grid-Tied Inverter

Energies, 2018
In a single-phase grid-tied inverter, the direct current (DC) offset error included in the measured grid side phase current has various causes, such as a non-ideal current sensor, unbalanced power supply of an operational amplifier, and nonlinear ...
Jae Suk Lee, Seon-Hwan Hwang
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Symmetrical Component Decomposition of DC Distribution Systems

IEEE Transactions on Power Systems, 2018
Employing bipolar dc distribution systems introduces the possibility of imbalance in the system. To analyze these systems it is important to create novel modelling techniques. Therefore, this paper presents a method to decompose dc distribution systems into symmetrical components.
Nils H. van der Blij, Laura M. Ramirez-Elizondo, Matthijs T. J. Spaan, Pavol Bauer   +3 more
openaire   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes.

PLoS ONE, 2015
Bodily secretions, including breast milk and semen, contain factors that modulate HIV-1 infection. Since anal intercourse caries one of the highest risks for HIV-1 transmission, our aim was to determine whether colorectal mucus (CM) also contains factors
Martijn J Stax, Emily E I M Mouser, Thijs van Montfort, Rogier W Sanders, Henry J C de Vries, Henk L Dekker, Carolina Herrera, Dave Speijer, Georgios Pollakis, William A Paxton   +9 more
doaj   +1 more source

Quantum oscillations of rectified dc voltage as a function of magnetic field in an "almost" symmetric superconducting ring

, 2007
Periodic quantum oscillations of a rectified dc voltage Vdc(B) vs the perpendicular magnetic field B were measured near the critical temperature Tc in a single superconducting aluminum almost symmetric ring (without specially created circular asymmetry ...
A. A. Firsov, I. Zapata, J.E. Mooij, S. V. Dubonos, S.V. Dubonos, V. I. Kuznetsov   +5 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source