Results 211 to 220 of about 69,679 (307)

Open Diagnostic Reader (ODR): An affordable, modular 3D-printed platform for standardized imaging and quantitative analysis of rapid diagnostic tests. [PDF]

open access: yesHardwareX
Rogers E   +20 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

Entropy Decoding the Fundamental Law of Phase Competition in Glass Formation

open access: yesAdvanced Science, EarlyView.
We validate the integration of intermetallic and eutectic phases as initial phases for composition design. The phase competition mechanism in glass formation is quantitatively clarified based on the melting entropy of competing phases. Glass‐forming ability is modulated by tuning phase competition via the melting entropy of initial phases.
Benke Huo   +7 more
wiley   +1 more source

Dynamically Modified Flexible Zn Powder Anodes with Stable Performance at High Rate and High Zn Utilization

open access: yesAdvanced Science, EarlyView.
A dynamically shape‐variant liquid metal‐based network is integrated into Zn powder electrode, where intrinsic fluidity and structural adaptability of the liquid metal‐based network enable effective mitigation of dendritic growth, alleviation of stress accumulation, and prevention of Zn loss during Zn plating‐stripping processes.
Yuxuan Wang   +9 more
wiley   +1 more source

Electromagnetic Radiation Stimulated Learning in Perovskite Nickelates

open access: yesAdvanced Science, EarlyView.
ABSTRACT Biological plasticity refers to the ability of synapses to strengthen or weaken over time. These adaptive properties play a fundamental role in learning and memory, spanning many orders of magnitude in timescales. Short‐term plasticity (STP) arises from rapid correlative activity, while long‐term plasticity (LTP) is governed by slower ...
Ranjan Kumar Patel   +8 more
wiley   +1 more source

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