Results 51 to 60 of about 1,786,036 (302)

Impact of PWM strategies on RMS current of the DC-link Voltage Capacitor of a dual-three phase drive [PDF]

open access: yes, 2014
The major drawback of usual dual three-phase AC machines, when supplied by a Voltage Source Inverter (VSI), is the occurrence of extra harmonic currents which circulate in the stator windings causing additional losses and constraints on the power ...
ROUHANA, Najib   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Step Respons Motor DC by Using Compression Signal Method

open access: yesComTech, 2015
Output signal in the form of a step response of a DC motor can be obtained by providing the input signal to the motor in the form of a signal step directly. Step response obtained in this way usually contains a lot of noise.
Satrio Dewanto
doaj   +1 more source

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open access: yes, 2020
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Лусто И.И, Койпиш В.Г
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Online Monitoring Method for Capacitor Lifetime in Brushless DC Motor Drive Systems with DC-Link Series Switch

open access: yesWorld Electric Vehicle Journal
Brushless DC motors are often used as traction motors in electric vehicles due to their high power density and efficiency. The dc-link electrolytic capacitor is the most vulnerable part of the brushless DC motor drive system, and it determines the ...
Zhongquan Qian   +4 more
doaj   +1 more source

Elimination of output voltage oscillations in DC-DC converter using PWM with PI controller [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2010
In this paper the SIMULINK model of a PWM controlled DC-DC converter is modeled using switching function concept to control the speed of the DC motor. The presence of the voltage oscillation cycles due to higher switching frequency in the DC-DC converter
Sreenivasappa Veeranna Bhupasandra   +1 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

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