Results 51 to 60 of about 645,990 (304)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Analysis of the Power Supply Influence on the Universal Motor
Power Electronics and Drives, 2022 Due to their advantageous properties, universal motors are widely used in various applications and can be operated with both AC and DC voltage. Between main advantages of universal motors are their high starting torque, very compact design and high ...
Girovský Peter, Kaňuch Ján
doaj +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Advanced Drive System for DC Motor Using Multilevel DC/DC Buck Converter Circuit
IEEE Access, 2019 This paper presents a new topology of clamped diode multilevel DC/DC buck power converter for a DC motor system. The proposed converter circuit consists of four cascaded MOSFET power switches with three clamping diodes and four voltage sources (voltage ...
Ali Ahmed Adam Ismail, A. Elnady
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Step Respons Motor DC by Using Compression Signal Method
ComTech, 2015 Output signal in the form of a step response of a DC motor can be obtained by providing the input signal to the motor in the form of a signal step directly. Step response obtained in this way usually contains a lot of noise.
Satrio Dewanto
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
World Electric Vehicle JournalBrushless DC motors are often used as traction motors in electric vehicles due to their high power density and efficiency. The dc-link electrolytic capacitor is the most vulnerable part of the brushless DC motor drive system, and it determines the ...
Zhongquan Qian +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source