Characterizing Cutaneous α-Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes. [PDF]
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Jin Y +8 more
europepmc +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
PROTOTYPE SISTEM KENDALI KECEPATAN MOTOR DC DENGAN PROPORTIONAL INTEGRAL DERIVATIVE (PID) CONTROLLER
Motor DC merupakan salah satu jenis aktuator yang cukup banyak digunakan dalam bidang industri, misalnya industri pembuatan kue, yang menggunakan motor DC pada mesin pencampuran bahan kue, dalam proses pencampuran bahan kue harus disesuaikan antara ...
Fahri Firdaus +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Robust Tracking Controller for a DC/DC Buck-Boost Converter–Inverter–DC Motor System
This paper has two aims. The first is to develop a robust hierarchical tracking controller for the DC/DC Buck-Boost–inverter–DC motor system.
Eduardo Hernández-Márquez +6 more
doaj +1 more source
Design and PLC Implementation for Speed Control of DC Motor using Fuzzy Logic [PDF]
In this article, a speed control of DC motor is designed and illustrated using fuzzy logic-based programmable logic controller (PLC). The DC motor is an attractive part of electrical equipment in many industrial applications requiring variable speed and ...
J. Rostami Monfared, M. Fazeli, Y. Lotfi
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
DESIGNING A WINDOWS PROGRAM FOR CONTROLLING DC-MOTORS USING MICROSOFT VISUAL STUDIO AND ARDUINO IDE
This case study wishes to highlight the advantages of using a Windows based PC to control a DC Motor for applications in small projects, the DC Motor being driven by an Arduino Uno board.
Theodor - Andrei Popescu +1 more
doaj +4 more sources
Speed Control of DC Motor using AC/AC/DC Converter Based on Intelligent Techniques
This paper describes the application of ac/ac/dc and ac/dc converters to control the speed of a separately excited DC motor. Artificial neural network and PI controller are trained to select the desired values of firing angles for triggering thyristors ...
Rakan K. Antar
doaj +1 more source

