Results 161 to 170 of about 41,420 (267)

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

open access: yesAdvanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed   +15 more
wiley   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

open access: yesAngewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo   +11 more
wiley   +2 more sources

An Intelligent Microfluidics Enabled by Data‐Driven Deep Learning‐Based Microrobot‐Assisted Flow Manipulation

open access: yesAdvanced Intelligent Systems, EarlyView.
An AI‐enabled micromixing framework is developed by integrating cGAN with Bayesian optimization for predictive control of microrobot‐driven flow manipulation. Through this framework, the spatiotemporal evolution of micromixing is learned directly from experimental images, while rapid identification of optimized microrobot actuation strategies is ...
Dineshkumar Loganathan, Chia‐Yuan Chen
wiley   +1 more source

Retraction Note: An experimental investigation of unique high stepup boost converter for electric vehicle and solar photovoltaic. [PDF]

open access: yesSci Rep
Mariprasath T   +7 more
europepmc   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc   +7 more
wiley   +1 more source

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang   +16 more
wiley   +1 more source

Advanced FCS-MPC strategy for optimized control and efficiency in photovoltaic inverters. [PDF]

open access: yesSci Rep
Dekhane A   +6 more
europepmc   +1 more source

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