Results 101 to 110 of about 113,946 (294)

Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning

open access: yesAdvanced Intelligent Systems, EarlyView.
A fundamental mucus cleaning mechanism is reported, which utilizes both artificial cilia mechanical sweeping and suction‐based mucus cleaning. A novel haptic feedback interface for the artificial cilia provides touch feedback on tissue contact, enhancing operator control and safety.
Zhongming Lyu   +7 more
wiley   +1 more source

Real‐World Outcomes of FLAG‐Ida Regimen in 1079 Adult Patients With First Relapsed/Refractory AML: A PETHEMA Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In a large multicenter real‐world cohort, we aimed to evaluate outcomes of FLAG‐Ida salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) and validated the SALFLAGE prognostic score. We analyzed 1079 adults with R/R AML treated across 112 PETHEMA institutions over 26 years (1998–2024), including patients with primary ...
Gaspar Aspas Requena   +49 more
wiley   +1 more source

An Efficient Lossless ROI Image Compression Using Wavelet-Based Modified Region Growing Algorithm

open access: yesJournal of Intelligent Systems, 2018
Nowadays, medical imaging and telemedicine are increasingly being utilized on a huge scale. The expanding interest in storing and sending medical images brings a lack of adequate memory spaces and transmission bandwidth.
Sreenivasulu P., Varadarajan S.
doaj   +1 more source

Initial experience of DCTs [PDF]

open access: yesBritish Dental Journal, 2020
Mehdizadeh, R.   +5 more
openaire   +2 more sources

Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1‐mediated P53 ubiquitination

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Based on a dermis fibroblast Gorab knockout mouse model, this study revealed that Gorab deficiency promotes skin aging by influencing RCHY1, causing a decrease in P53 ubiquitination, damaging the activity of HDAC2, further resulting in the accumulation of aging‐related proteins (P53, P21, P16) and a reduction in extracellular matrix (ECM) components ...
Yanhong Li   +7 more
wiley   +1 more source

DCT/IDCT-based interpolation for channel estimation in OFDM systems(OFDM系统DCT/IDCT插值信道估计算法)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2008
导频辅助信道估计是OFDM系统常用的信道估计算法,本文研究基于变换域的导频辅助信道估计算法.在DFT插值法的基础上,提出了基于离散余弦变换(DCT)的信道估计方法.仿真结果表明,该插值算法的MSE和SER性能优于DFT方法.与MMSE算法相比,该插值算法计算复杂度低,易于物理实现.
JINNing(金宁)   +2 more
doaj   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

open access: yesAnnals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa   +6 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

open access: yesThe Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum   +3 more
wiley   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid   +34 more
wiley   +1 more source

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