Results 1 to 10 of about 19 (19)
The FASEB Journal, Volume 37, Issue 12, December 2023., 2023 Olfactory dysfunction is one of the most prevalent symptoms of Parkinson's disease preceding clinical onset by up to a decade. However, PD models focus mainly on motor symptoms and nigrostriatal degeneration. Here, we characterize cultured olfactory bulb organotypic slices and cells and explore the effect of DOPAL, a metabolite of dopamine.
Enrico Bagnoli +6 more
wiley +1 more source
Guidelines for mouse and human DC generation
European Journal of Immunology, Volume 53, Issue 11, November 2023., 2023 The article on DC generation is part of the DC Guidelines article collection providing methods for the isolation of mouse and human cellular sources that can be cultured with different growth factors to generate the known subsets of DC. Abstract This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state ...
Manfred B. Lutz +25 more
wiley +1 more source
Journal of Neuroendocrinology, Volume 35, Issue 10, October 2023., 2023 The purpose of the present study was to understand the function of sexually dimorphic OXTR neurons. The study revealed that the activity of the sexually dimorphic OXTR neurons is necessary for maternal behavior in female mice. Abstract Maternal care is crucial for the survival and development of offspring.
Kaustubh Sharma +5 more
wiley +1 more source
Statistics in Medicine, Volume 42, Issue 22, Page 4028-4042, 30 September 2023., 2023 Abstract Recurrent events are commonly encountered in biomedical studies. In many situations, there exist terminal events, such as death, which are potentially related to the recurrent events. Joint models of recurrent and terminal events have been proposed to address the correlation between recurrent events and terminal events.
Fang Niu, Cheng Zheng, Lei Liu
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 6, Page 3558-3574, June 2023., 2023 Long‐horned grasshoppers are consumed in over 21 African countries. Crude protein (28%–45%), crude fat (41%–54%), and energy (582–644 Kj/100 g) of grasshoppers are comparable to that of plant and animal origins. Grasshopper meal could be considered as functional food ingredients capable of supplying adequate essential macro‐ and micronutrients ...
Margaret Kababu +4 more
wiley +1 more source
Monoclonal antibodies for the treatment of squamous cell carcinoma: A literature review
Cancer Reports, Volume 6, Issue 5, May 2023., 2023 Abstract Background Squamous cell carcinoma (SCC) is a relatively common and heterogenous malignancy of different organs, such as the skin, esophagus, and lungs. Although most cases experience good survival with surgical methods, management of advanced types of the disease remains challenging.
Amirhossein Tamimi +8 more
wiley +1 more source
Rare, common, alien and native species follow different rules in an understory plant community
Ecology and Evolution, Volume 12, Issue 3, March 2022., 2022 Many parks and forests have experienced centuries of multispecies invasions. Using a multi‐site turnover metric, we differentiate between the structure and drivers of the geographically rare and common alien and native understorey plants. Distinct differences were identified between the alien and native species; namely that natives were driven by ...
Sarah Reeve +5 more
wiley +1 more source
International Journal of Cancer, Volume 149, Issue 5, Page 1181-1188, 1 September 2021., 2021 Abstract The tumor‐stroma ratio (TSR) has proven to be a strong prognostic factor in breast cancer, demonstrating better survival for patients with stroma‐low tumors. Since the role of the TSR as a predictive marker for neoadjuvant chemotherapy outcome is yet unknown, this association was evaluated for HER2‐negative breast cancer in the prospective ...
Sophie C. Hagenaars +12 more
wiley +1 more source
STEM CELLS Translational Medicine, Volume 10, Issue 5, Page 725-742, May 2021., 2021 Schematic representation of the functional properties acquired by human induced pluripotent stem cells (hiPSCs) following GLYPICAN‐4 (GPC4) downregulation versus control. This includes impaired in vivo tumorigenesis as assessed by flank xenografts, and enhanced differentiation toward ventral midbrain dopaminergic (VMDA) neuron progenitors both in vitro
Serena Corti +10 more
wiley +1 more source
Comorbidities and complications in adults with pyruvate kinase deficiency
European Journal of Haematology, Volume 106, Issue 4, Page 484-492, April 2021., 2021 Abstract Objectives Pyruvate kinase (PK) deficiency is caused by PKLR gene mutations, leading to defective red blood cell glycolysis and hemolytic anemia. Rates of comorbidities and complications by transfusion history and relative to the general population remain poorly quantified.
Audra N. Boscoe +16 more
wiley +1 more source