Results 21 to 30 of about 26,606 (61)

Evaluation of Strength and Irradiated Movement Pattern Resulting from Trunk Motions of the Proprioceptive Neuromuscular Facilitation

Rehabilitation Research and Practice, Volume 2012, Issue 1, 2012., 2012
Introduction. The proprioceptive neuromuscular facilitation (PNF) is a physiotherapeutic concept based on muscle and joint proprioceptive stimulation. Among its principles, the irradiation is the reaction of the distinct regional muscle contractions to the position of the application of the motions. Objective.
Luciana Bahia Gontijo, Polianna Delfino Pereira, Camila Danielle Cunha Neves, Ana Paula Santos, Dionis de Castro Dutra Machado, Victor Hugo do Vale Bastos, Luc Vanhees   +6 more
wiley   +1 more source

Strong Trinucleotide Circular Codes

International Journal of Combinatorics, Volume 2011, Issue 1, 2011., 2011
Recently, we identified a hierarchy relation between trinucleotide comma‐free codes and trinucleotide circular codes (see our previous works). Here, we extend our hierarchy with two new classes of codes, called DLD and LDL codes, which are stronger than the comma‐free codes.
Christian J. Michel, Giuseppe Pirillo, Toufik Mansour   +2 more
wiley   +1 more source

Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease

Acta Neuropathologica
Parkinson’s disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are no early-stage molecular biomarkers for diagnosis, prognosis prediction, or monitoring therapeutic response.
J. Rutledge, B. Lehallier, P. Zarifkar, P. M. Losada, Marian Shahid-Besanti, D. Western, P. Gorijala, S. Ryman, Maya V Yutsis, Gayle K. Deutsch, E. Mormino, Alexandra N. Trelle, Anthony D. Wagner, Geoffrey A. Kerchner, Lu Tian, C. Cruchaga, Victor W. Henderson, T. Montine, P. Borghammer, Tony Wyss-Coray, K. Poston   +20 more
semanticscholar   +1 more source

Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary

International Journal of Molecular Sciences, 2019
The origin of serotonin in the ovary is the key question for understanding mechanisms of serotonergic regulation of reproductive function. We performed a study of the expression and functional activity of the serotonin transporter (SERT) and the enzyme ...
D. A. Nikishin, N. M. Alyoshina, M. Semenova, Y. B. Shmukler   +3 more
semanticscholar   +1 more source

Current Use of Nucleoside Analogues in the Treatment of HIV Infection

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 5, Issue E, Page 21E-26E, 1994., 1994
Nucleoside analogues continue to play a central role in the treatment of HIV infection. The recently published Concorde I.rial has been misinterpreted as demonstrating a Jack of efficacy of zidovudine in the treatment of HIV disease. This is clearly not the case because zidovudine was prescribed to patients in both arms of the study. The Concorde study
Julio SG Montaner, Carlos Zala, Leila Spour   +2 more
wiley   +1 more source

Antifungal and Antiviral Cyclic Peptides from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020.

Journal of Agricultural and Food Chemistry, 2017
A new linear peptide simplicilliumtide I (1) and four new cyclic peptides simplicilliumtides J-M (2-5) together with known analogues verlamelins A and B (6 and 7) were isolated from the deep-sea-derived fungal strain Simplicillium obclavatum EIODSF 020 ...
X. Liang, Xu-hua Nong, Zhong-Hui Huang, S. Qi   +3 more
semanticscholar   +1 more source

NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

Journal of Neuroinflammation, 2015
BackgroundAging is associated with a decline in stem cell proliferation that is thought to be a result of dysregulated signaling in the neurogenic niche. This results in a diminished and less efficient pool of progenitors.
Antwoine Flowers, Jea-Young Lee, Sandra A. Acosta, C. Hudson, B. Small, C. Sanberg, P. Bickford   +6 more
semanticscholar   +2 more sources

Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy

Scientific Reports, 2018
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail, Masashi Miyao, H. Kotani, C. Kawai, Hirozo Minami, H. Abiru, Keiji Tamaki   +6 more
semanticscholar   +1 more source

Protective effect of green perilla-derived chalcone derivative DDC on amyloid β protein-induced neurotoxicity in primary cortical neurons.

Biological and Pharmaceutical Bulletin, 2019
Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki, Naotaka Izuo, Yasuhiko Izumi, Yuki Takada‐Takatori, A. Akaike, T. Kume   +5 more
semanticscholar   +1 more source

Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury

Molecular Pain, 2018
Extracellular regulated protein kinase (ERK) pathway activation in astrocytes and neurons has been reported to be critical for neuropathic pain development after chronic constriction injury.
Liang Zhao, Dan Li, Nan Liu, Lu Liu, Zhuo Zhang, Chao Gao, H. Kawano, Fang-yuan Zhou, Hong-peng Li   +8 more
semanticscholar   +1 more source