Results 21 to 30 of about 888,040 (102)

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

The FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo, Juan García‐Sáez, María Figueroa‐Fuentes, Annalisa Addante, Cesáreo Roncero, Nerea Lazcanoiturburu, Beatriz Pacheco, Julián Sanz, Cristina Gato, Eva Fernández‐Calderón, María de la O López, Águeda González‐Rodríguez, Almudena Porras, Flavio Maina, Isabel Fabregat, Blanca Herrera, Aránzazu Sánchez   +16 more
wiley   +1 more source

Symbiosis‐associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula

New Phytologist, EarlyView.
Summary To address a critical gap in understanding amino acid transport in legume–Rhizobium symbiosis, we investigated the role of symbiosis‐associated USUALLY MULTIPLE ACIDS MOVE IN AND OUT TRANSPORTERS (UMAMITs) in Medicago truncatula nodulation.
Courtney S. Winning, María Isabel Rubia, Wei Liu, Daniel Bronitt, Ángel María Zamarreño, José María García‐Mina, Penelope Smith, Estíbaliz Larrainzar, Michael A. Djordjevic   +8 more
wiley   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, Volume 13, Issue 9, 13 February 2026.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source

Ribcage Morphology in Native South American Populations From Different Altitudes: Insights From a Global Comparative Framework

American Journal of Human Biology, Volume 38, Issue 2, February 2026.
ABSTRACT Objectives Altitude shapes human morphology as highland populations must cope with cold and hypoxic environments. Although Andean highlanders have been proposed to exhibit larger and deeper ribcages, this idea is mainly based on research using disarticulated skeletal elements or non‐South American controls. The objective of this research is to
J. M. López‐Rey, M. D. D’Angelo del Campo, G. Bettera Marcat, M. Arrieta, M. Fabra, S. Salega, P. Mercolli, V. Seldes, D. García‐Martínez, M. Bastir   +9 more
wiley   +1 more source

Allelopathy as a Strategy for Biological Invasion: Calotropis procera and Its Impact on Plant Succession

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Stages of the study on the allelopathic potential of Calotropis procera (Aiton) W. T. Aiton. The image shows the collection of plant material, the decomposition of organic matter, the identification of bioactive compounds, and the effects on the germination of Handroanthus impetiginosus (Mart. ex DC.) Mattos.
Bruno Melo de Alcântara, Paulo Henrique Calixto Santana, Felipe Rufino dos Santos, José Weverton Almeida‐Bezerra, José Galberto Martins da Costa, Delmira da Costa Silva, Cláudia Maria Furlan, Maria Arlene Pessoa da Silva   +7 more
wiley   +1 more source

A Case Report of Promising Response to Combination Therapy With an Immune Checkpoint Inhibitor (Pembrolizumab) and Multi‐Targeted Tyrosine Kinase Inhibitor (Pazopanib) in Metastatic De‐Differentiated Chondrosarcoma

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background We present the case of 72–year‐old male with metastatic de‐differentiated chondrosarcoma (“DDCS”). DDCS is a rare soft tissue cancer that carries a dismal prognosis in the metastatic stage, and is resistant to both traditional chemotherapy and radiotherapy. There is a distinct lack of proven systemic therapies. Case This case report
Matthew Youssef, Peter Grimison
wiley   +1 more source

Management Strategies and Agricultural Calendars for Forage Production in Semi‐Arid Brazil Using AquaCrop

Irrigation and Drainage, Volume 75, Issue 1, Page 411-424, February 2026.
ABSTRACT Forage production in semi‐arid regions of Brazil is limited by water deficit. This study aimed to identify the most adapted and efficient production systems and define their agricultural calendars for the semi‐arid region of Brazil. Twenty‐nine production arrangements that included different cropping conditions, plant density, plant cycles ...
Antonio Gebson Pinheiro, Cleber Pereira Alves, Carlos André Alves de Souza, George do Nascimento Araújo Júnior, Alexandre Maniçoba da Rosa Ferraz Jardim, Regina Crisóstomo Grangeiro Pereira, José Edson Florentino de Morais, Luciana Sandra Bastos de Souza, Daniela de Carvalho Lopes, Antonio José Steidle Neto, Adriano Nascimento Simões, Fleming Sena Campos, Kaique Renan da Silva Salvador, João Emanoel Ambrósio Gomes, Enio Farias de Franca e Silva, Thieres George Freire da Silva   +15 more
wiley   +1 more source

Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic

Microbial Biotechnology, Volume 19, Issue 2, February 2026.
Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley   +1 more source