Results 91 to 100 of about 79,876 (114)

The ESCRT protein CHMP5 promotes T cell leukemia by enabling BRD4-p300-dependent transcription. [PDF]

open access: yesNat Commun
Umphred-Wilson K   +12 more
europepmc   +1 more source

Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism. [PDF]

open access: yesJ Exp Clin Cancer Res
Ibello E   +16 more
europepmc   +1 more source
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Sphingomyelin-based PEGylation Cu(DDC)2 Liposomes Prepared via the Dual Function of Cu2+ for Cancer Therapy: Facilitating DDC Loading and Exerting Synergistic Antitumor Effects.

International journal of pharmaceutics, 2022
The old alcohol-aversion drug disulfiram (DSF) has aroused wide attention as a drug repurposing strategy in terms of cancer therapy because of the high antitumor efficacy in combination with copper ion.
Hao Liu   +9 more
semanticscholar   +1 more source

Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response

Journal of Pathology, 2022
Despite the well‐known hepatoprotective role of the epidermal growth factor receptor (EGFR) pathway upon acute damage, its specific actions during chronic liver disease, particularly cholestatic injury, remain ambiguous and unresolved.
Nerea Lazcanoiturburu   +19 more
semanticscholar   +1 more source

Geniposide suppresses liver injury in a mouse model of DDC‐induced sclerosing cholangitis

Phytotherapy Research, 2021
Sclerosing cholangitis, characterized by biliary inflammation, fibrosis, and stricturing, remains one of the most challenging conditions of clinical hepatology. Geniposide (GE) has anti‐inflammatory, hepatoprotective, and cholagogic effects.
Min Wen   +6 more
semanticscholar   +1 more source

ZIF-301 MOF/6FDA-DAM polyimide mixed-matrix membranes for CO2/CH4 separation

Separation and Purification Technology, 2021
Compared with traditional separation methods, membrane-based technology shows advantages in energy efficiency for natural gas purification. To overcome the performance trade-off of conventional polymeric membranes, in this study, ZIF-301 MOF was employed
Zhenggang Wang   +7 more
semanticscholar   +1 more source

Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (Telomelysin) with radiotherapy in oesophageal cancer patients unfit for standard treatments.

European Journal of Cancer, 2021
PURPOSE OBP-301 (Telomelysin) is an attenuated type-5 adenovirus that contains the human telomerase reverse transcriptase promoter to regulate viral replication.
Y. Shirakawa   +14 more
semanticscholar   +1 more source

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