Results 21 to 30 of about 72,479 (112)

Organ Transplantation: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis

open access: yesAntimicrobial Agents and Chemotherapy, 2019
Bacteriophage-derived lysins are cell-wall-hydrolytic enzymes that represent a potential new class of antibacterial therapeutics in development to address burgeoning antimicrobial resistance.
C. Indiani   +7 more
semanticscholar   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Metformin and insulin exacerbate one‐carbon metabolism deficits in pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas

open access: yesThe Journal of Physiology, Volume 603, Issue 19, Page 5751-5775, October 1, 2025.
Abstract figure legend Uteroplacental insufficiency (growth restricted) or sham (Control) surgery was performed on embryonic day (E)18 in Wistar–Kyoto rats. Female F1 offspring were mated and restricted dams received daily metformin, insulin or vehicle from E13.
Dayna A. Zimmerman   +11 more
wiley   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen   +4 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

The pivotal role of mass spectrometry in transition metal‐based photocatalyst research for solar‐driven energy conversion and water purification advancements

open access: yesBulletin of the Korean Chemical Society, Volume 46, Issue 4, Page 381-412, April 2025.
This review explores recent advancements in the integration of solar energy conversion and water remediation with mass spectrometry as an analytical technique. We examine Ti‐based photocatalysts for their roles in energy conversion and water purification, utilizing mass spectrometric analysis to evaluate the efficiency of these mechanisms.
Haheun Yoo   +4 more
wiley   +1 more source

Opinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) relating to an analysis of the health risks associated with exposure to caterpillars with stinging hairs and the development of management recommendations

open access: yesFood Risk Assess Europe, Volume 3, Issue 2, April 2025.
Abstract Several species of Lepidoptera with caterpillars bearing urticating hairs are increasing their range in metropolitan France from year to year, such as the pine processionary (Thaumetopoea pityocampa Denis et Schiffermüller 1775) whose presence was historically limited to the south of France, and which is gradually being observed in the north ...
Nicolas Desneux   +105 more
wiley   +1 more source

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