Results 31 to 40 of about 72,479 (112)
Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki +5 more
semanticscholar +1 more source
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail +6 more
semanticscholar +1 more source
Abstract Introduction WHO's Integrated Care for Older People (ICOPE) proposes we measure the functional construct of intrinsic capacity (IC) to monitor and identify individuals with age‐associated vulnerabilities. Assessments of IC may be useful to address the evolving, non‐HV care needs of ageing people with HIV (PWH).
Reena Rajasuriar +16 more
wiley +1 more source
A randomized trial of inhaled levodopa (CVT‐301) for motor fluctuations in Parkinson's disease
Although levodopa is the most effective oral PD therapy, many patients experience motor fluctuations, including sudden loss of dose effect and delayed benefit. CVT‐301 is a levodopa inhalation powder with the potential for rapid onset of action.
P. LeWitt +10 more
semanticscholar +1 more source
Abstract In 2018, a significant neural tube defects (NTD) signal was reported after pre‐conceptional exposure to dolutegravir, but was not confirmed in further analysis. Since 2019, dolutegravir‐based regimen, an integrase inhibitor (INI), is recommended by WHO as the most‐effective first‐line therapy in all patients living with HIV.
Laura Saint‐Lary +3 more
wiley +1 more source
The authors provide an in‐depth exploration of recent advancements in ultrasound imaging, computed tomography imaging, magnetic resonance imaging, nuclear medicine imaging, radiomics, and artificial intelligence within the field of liver fibrosis research.
Wenpeng Huang, Yushuo Peng, Lei Kang
wiley +1 more source
Luteolin inhibited proliferation and induced apoptosis of prostate cancer cells through miR-301
Luteolin is a falvonoid compound derived from Lonicera japonica Thunb. Numerous reports have demonstrated that luteolin has anticancer effects on many kinds of tumors.
Kun Han +9 more
semanticscholar +1 more source
The Sins of the Fathers: Targeted Sanctions against Family Members of Primary Targets
Targeted sanctions, such as asset freezes and travel bans, are an increasingly popular response to a wide array of wrongdoing. This article considers an especially problematic aspect of contemporary sanctions law and practice that has received little attention so far, namely the imposition of sanctions on the family members of the primary target.
Anton Moiseienko
wiley +1 more source
Background: CVT-301, an inhaled levodopa (LD) formulation, is under development for relief of OFF periods in Parkinson's disease (PD). Previously, we reported that CVT-301 improved OFF symptoms relative to placebo.
P. LeWitt +5 more
semanticscholar +1 more source

