Results 1 to 10 of about 19 (19)

Total Synthesis of 1”‐ and 2”‐Hydroxycannabidiol Metabolites

open access: yesChemistrySelect, Volume 8, Issue 45, December 5, 2023., 2023
A new multistep protocol, comprising four steps, was implemented to prepare 1”‐hydroxycannabidiol and 2”‐hydroxycannabidiol, two of the most important and investigated hydroxylated cannabidiol metabolites. The reactions are easily feasible, and metabolites were isolated, in 24 % and 28 % of overall yield respectively, as mixtures of epimers.
Benedetta Bassetti   +4 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +28 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander   +27 more
wiley   +1 more source

Death receptor 3 is involved in preeclampsia through regulating placental trophoblast cell physiology by inactivating the PI3K/AKT pathway

open access: yesImmunity, Inflammation and Disease, Volume 11, Issue 9, September 2023., 2023
The present study was to illustrate the biological roles of death receptor 3 (DR3) in placental trophoblast cells, as well as explain its relevant mechanisms. The findings revealed that DR3 is involved in preeclampsia (PE) through regulating placental trophoblast cell physiology via PI3K/AKT pathway, which might be a promising therapeutic target for PE
Cheng Yin   +7 more
wiley   +1 more source

Rotor orientation direction controls geometric curvature and chirality for assemblies of motor amphiphiles in water

open access: yesAggregate, Volume 4, Issue 2, April 2023., 2023
Herein, we show how aggregate geometric curvature and chirality of motor amphiphiles could be switched from bicontinuous calabashes to nanoribbons or from vesicles to nanoribbons by modulating rotor orientation direction with dual light/heat stimuli to influence spontaneous curvature in assemblies.
Yun‐Han Yang   +3 more
wiley   +1 more source

Protecting Earth and Space Industries from Orbital Debris: Implementing the Outer Space Treaty to Fill the Regulatory Vacuum in the FCC's Orbital Debris Guidelines

open access: yesAmerican Business Law Journal, Volume 60, Issue 1, Page 175-229, Spring 2023., 2023
The Outer Space Treaty (OST) is the foundation of all international space regulation. It establishes space as the province of all humankind and promotes its peaceful use and exploration for the benefit and in the interests of all countries. In 2020, the FCC released its “Mitigation of Orbital Debris in the New Space Age” guidelines for commercial ...
Michael B. Runnels
wiley   +1 more source

Commodity risk assessment of Prunus persica and P. dulcis plants from Türkiye

open access: yesEFSA Journal, Volume 21, Issue 1, January 2023., 2023
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by plants of Prunus persica and P.
EFSA Panel on Plant Health (PLH)   +31 more
wiley   +1 more source

Acanthopagrus oconnorae, a new species of seabream (Sparidae) from the Red Sea

open access: yesJournal of Fish Biology, Volume 101, Issue 4, Page 885-897, October 2022., 2022
Abstract A new species of sparid fish, Acanthopagrus oconnorae, is described based on 11 specimens collected in the shallow (0–1 m depth) mangrove‐adjacent sandflats of Thuwal, Saudi Arabia. The new species is distinguished from its congeners by the following combination of characters: second anal‐fin spine 12.8%–16.6% of standard length (SL); 3½ scale
Lucía Pombo‐Ayora   +7 more
wiley   +1 more source

Atopic dermatitis: pathogenesis and therapeutic intervention

open access: yesMedComm, Volume 5, Issue 12, December 2024.
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease, and its complex pathogenesis is closely linked to genetic and environmental factors, skin barrier dysfunction as well as immune dysfunction, which imposes a significant socioeconomic burden in all countries. The compromised function of the skin barrier leads to the release of alarm
Chengcheng Yue   +16 more
wiley   +1 more source

UEG Week 2023 Moderated Posters

open access: yes, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

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