Results 1 to 10 of about 539 (66)
Construction and Identification of Inflammation‐Related TF–mRNA–miRNA Coexpression Network and Immune Infiltration in Parkinson’s Disease [PDF]
Parkinson's Disease, Volume 2025, Issue 1, 2025.Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Inflammation, marked by the infiltration of inflammatory mediators and the proliferation of inflammatory cells, is closely linked to PD. This study aims to identify and validate inflammation‐related biomarkers in PD and construct a TF–mRNA–miRNA ...
Zhuzhen Shen +4 more
wiley +2 more sources
Atopic dermatitis: pathogenesis and therapeutic intervention [PDF]
MedComm, Volume 5, Issue 12, December 2024.Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease, and its complex pathogenesis is closely linked to genetic and environmental factors, skin barrier dysfunction as well as immune dysfunction, which imposes a significant socioeconomic burden in all countries. The compromised function of the skin barrier leads to the release of alarm
Chengcheng Yue +16 more
wiley +2 more sources
Total Synthesis of 1”‐ and 2”‐Hydroxycannabidiol Metabolites
ChemistrySelect, Volume 8, Issue 45, December 5, 2023., 2023 A new multistep protocol, comprising four steps, was implemented to prepare 1”‐hydroxycannabidiol and 2”‐hydroxycannabidiol, two of the most important and investigated hydroxylated cannabidiol metabolites. The reactions are easily feasible, and metabolites were isolated, in 24 % and 28 % of overall yield respectively, as mixtures of epimers.
Benedetta Bassetti +4 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Enzymes
British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +28 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
Cell Proliferation, EarlyView.This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan +5 more
wiley +1 more source
Journal of Polymer Science, Volume 63, Issue 9, Page 2113-2121, 1 May 2025.Copolymerization with arylamine initially reduces the mobility of the fluorene homopolymer due to trapping but increases with higher arylamine content, demonstrating that mobility in these copolymers is governed by chemical composition. While fluorene β‐phase conformation plays a minor role in transport, it strongly influences emission.
Nikol T. Lambeva +3 more
wiley +1 more source
Bulletin of the Korean Chemical Society, Volume 46, Issue 4, Page 381-412, April 2025.This review explores recent advancements in the integration of solar energy conversion and water remediation with mass spectrometry as an analytical technique. We examine Ti‐based photocatalysts for their roles in energy conversion and water purification, utilizing mass spectrometric analysis to evaluate the efficiency of these mechanisms.
Haheun Yoo +4 more
wiley +1 more source
Gene therapy for genetic diseases: challenges and future directions
MedComm, Volume 6, Issue 2, February 2025.The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie +4 more
wiley +1 more source
Small, Volume 21, Issue 3, January 22, 2025.A continuous‐output ion thermoelectric generator based on the redox reaction of Cu/Cu2+ embedded in a flexible MXene/PVA hydrogel is developed to harvest near‐room‐temperature heat. The thermopower is enhanced by reducing the diffusivity of ions via the addition of MXene.
Dezhuang Ji +6 more
wiley +1 more source