Results 21 to 30 of about 102,839 (113)

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

miR‐330 suppresses EMT and induces apoptosis by downregulating HMGA2 in human colorectal cancer

Journal of Cellular Physiology, 2019
MicroRNAs (miRNAs) are important molecular regulatorsof cellular signaling and behavior. They alter gene expression by targeting messenger RNAs, including those encoding transcriptional regulators, such as HMGA2.
B. Mansoori, A. Mohammadi, Sanaz Naghizadeh, M. Gjerstorff, D. Shanehbandi, Solmaz Shirjang, S. Najafi, U. Holmskov, V. Khaze, Pascal H. G. Duijf, B. Baradaran   +10 more
semanticscholar   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Power source, data retrieval method, and attachment type affect success of dorsally mounted tracking tag deployments in 37 species of shorebirds

Journal of Avian Biology, Volume 2025, Issue 6, November 2025.
Animal‐borne trackers are commonly used to study bird movements, including in long‐distance migrants such as shorebirds. Selecting a tracker and attachment method can be daunting, and methodological advancements often have been made by trial and error and conveyed by word of mouth.
Emily L. Weiser, Richard B. Lanctot, Daniel R. Ruthrauff, Sarah T. Saalfeld, T. Lee Tibbitts, José M. Abad‐Gómez, Joaquin Aldabe, Juliana Bosi de Almeida, José A. Alves, Guy Q.A. Anderson, Phil F. Battley, Heinrich Belting, Joël Bêty, Kristin Bianchini, Mary Anne Bishop, Roeland A. Bom, Katharine Bowgen, Glen S. Brown, Stephen C. Brown, Leandro Bugoni, Niall H.K. Burton, David R. Bybee, Camilo Carneiro, Gabriel Castresana, Ying‐Chi Chan, Chi‐Yeung Choi, Katherine S. Christie, Nigel A. Clark, Jesse R. Conklin, Medardo Cruz‐López, Stephen J. Dinsmore, Steve G. Dodd, David C. Douglas, Luke J. Eberhart‐Hertel, Willow B. English, Harry T. Ewing, Fernando A. Faria, Samantha E. Franks, Richard A. Fuller, Robert E. Gill Jr, Marie‐Andrée Giroux, Cheri L. Gratto‐Trevor, David J. Green, Rhys E. Green, Ros M.W. Green, Tómas G. Gunnarsson, Jorge S. Gutiérrez, Autumn‐Lynn Harrison, C. Alex Hartman, Chris J. Hassell, Sarah A. Hoepfner, Jos C. E. W. Hooijmeijer, James A. Johnson, Oscar W. Johnson, Bart Kempenaers, Marcel Klaassen, Eva M.A. Kok, Johannes Krietsch, Clemens Küpper, Andy Y. Kwarteng, Eunbi Kwon, Jean‐Francois Lamarre, Christopher J. Latty, Nicolas Lecomte, A.H. Jelle Loonstra, Zhijun Ma, Lucas Mander, Christopher Marlow, Peter P. Marra, Jose A. Masero, Laura A. McDuffie, Rebecca L. McGuire, Johannes Melter, David S. Melville, Verónica Méndez, Tyler J. Michels, Christy A. Morrissey, Tong Mu, David J. Newstead, Gary W. Page, Allison K. Pierce, Theunis Piersma, Márcio Repenning, Brian H. Robinson, Afonso D. Rocha, Danny I. Rogers, Amy L. Scarpignato, Shiloh Schulte, Emily S. Scragg, Nathan R. Senner, Paul A. Smith, Audrey R. Taylor, Rachel C. Taylor, Böðvar Þórisson, Mihai Valcu, Mo A. Verhoeven, Lena Ware, Nils Warnock, Michael F. Weber, Lucy J. Wright, Michael B. Wunder   +100 more
wiley   +1 more source

Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary

International Journal of Molecular Sciences, 2019
The origin of serotonin in the ovary is the key question for understanding mechanisms of serotonergic regulation of reproductive function. We performed a study of the expression and functional activity of the serotonin transporter (SERT) and the enzyme ...
D. A. Nikishin, N. M. Alyoshina, M. Semenova, Y. B. Shmukler   +3 more
semanticscholar   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

miR-330-5p targets SPRY2 to promote hepatocellular carcinoma progression via MAPK/ERK signaling

Oncogenesis, 2018
MicroRNAs (miRNAs) have been identified as critical modulators of cell proliferation and growth, which are the major causes of cancer progression including hepatocellular carcinoma (HCC).

semanticscholar   +1 more source

MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer

Aging, 2019
Brain metastasis (BM) is associated with poor prognosis in patients with non-small cell lung cancer (NSCLC). We sought to identify microRNAs (miRNAs) that could serve as biomarkers to differentiate NSCLC patients with and without BM.
C. Wei, Ruiguang Zhang, Q. Cai, Xican Gao, F. Tong, Ji-hua Dong, Yu Hu, Gang Wu, Xiaorong Dong   +8 more
semanticscholar   +1 more source

Leukocyte count and new‐onset diabetes mellitus in people with HIV: A longitudinal study

HIV Medicine, Volume 26, Issue 10, Page 1585-1599, October 2025.
Abstract Objectives The risk of diabetes mellitus (DM) is increased in people with HIV. Chronic inflammation contributes to DM risk. High leukocytes are associated with DM in the general population, but in people with HIV, evidence of a leukocyte–DM association is limited. Methods We included participants of the Swiss HIV Cohort Study with new‐onset DM
Sophia C. Meyer, Zoe Klein, Isabella C. Schoepf, Christian W. Thorball, Marco Labarile, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Matthias Cavassini, Annalisa Marinosci, Jacques Fellay, Huldrych F. Günthard, Roger D. Kouyos, Bruno Ledergerber, Philip E. Tarr, the Swiss HIV Cohort Study, I Abela, K Aebi‐Popp, A Anagnostopoulos, M Battegay, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, CA Fux, HF Günthard, A Hachfeld, D Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, patient representatives, CR Kahlert, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, N Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, G Pantaleo, M Perreau, A Rauch, L Salazar‐Vizcaya, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +75 more
wiley   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source