Results 21 to 30 of about 101,997 (112)

The Tumor-Suppressive Human Circular RNA CircITCH Sponges miR-330-5p to Ameliorate Doxorubicin-Induced Cardiotoxicity Through Upregulating SIRT6, Survivin, and SERCA2a

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Doxorubicin is one of the most potent antitumor agents available; however, its clinical use is restricted because it poses a risk of severe cardiotoxicity.
Dong Han, Yongjun Wang, Yabin Wang, Xinchun Dai, Tingwen Zhou, Jiangwei Chen, B. Tao, Jibin Zhang, F. Cao   +8 more
semanticscholar   +1 more source

Circ_0008532 promotes bladder cancer progression by regulation of the miR-155-5p/miR-330-5p/MTGR1 axis

Journal of experimental & clinical cancer research : CR, 2020
Background Circular RNAs (circRNAs) have been associated with bladder cancer (BC), but the specific underlying molecular mechanism of their association with BC development has not been fully explored.
Liang Chen, Xiong Yang, Jun Zhao, M. Xiong, Raya Almaraihah, Zhaohui Chen, Teng Hou   +6 more
semanticscholar   +1 more source

circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma

Journal of experimental & clinical cancer research : CR, 2019
Growing evidences indicate that circular RNAs (circRNAs) play an important role in the regulation of biological behavior of tumor. We aim to explore the role of circRNA in glioma and elucidate how circRNA acts.
Jiansheng Chen, Taoliang Chen, Yubo Zhu, Yan Li, Yuxuan Zhang, Yun Wang, Xiao Li, X. Xie, Jihui Wang, Min Huang, Xinlin Sun, Yiquan Ke   +11 more
semanticscholar   +1 more source

Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

International Journal of Molecular Sciences, 2020
Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy.
P. Artemaki, Maria Papatsirou, Michaela A. Boti, P. Adamopoulos, S. Christodoulou, D. Vassilacopoulou, A. Scorilas, C. Kontos   +7 more
semanticscholar   +1 more source

L-Dopa-Decarboxylase (DDC) Is a Positive Prognosticator for Breast Cancer Patients and Epinephrine Regulates Breast Cancer Cell (MCF7 and T47D) Growth In Vitro According to Their Different Expression of Gi- Protein- Coupled Receptors

International Journal of Molecular Sciences, 2020
A coherence between thyroid dysfunction and breast cancer incidence exists. Thyroid hormone metabolites bind to TAAR1 (trace amine-associated receptor 1) and through that modulate the serotonergic and dopaminergic system.
E. Tremmel, C. Kuhn, T. Kaltofen, T. Vilsmaier, D. Mayr, S. Mahner, N. Ditsch, U. Jeschke, A. Vattai   +8 more
semanticscholar   +1 more source

Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease

Acta Neuropathologica
Parkinson’s disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are no early-stage molecular biomarkers for diagnosis, prognosis prediction, or monitoring therapeutic response.
J. Rutledge, B. Lehallier, Pardis Zarifkar, P. M. Losada, M. Shahid-Besanti, D. Western, P. Gorijala, S. Ryman, M. Yutsis, Gayle K. Deutsch, E. Mormino, A. Trelle, Anthony D. Wagner, G. Kerchner, Lu Tian, C. Cruchaga, Victor W. Henderson, T. Montine, P. Borghammer, Tony Wyss-Coray, K. Poston   +20 more
semanticscholar   +1 more source

Circ-ZKSCAN1 regulates FAM83A expression and inactivates MAPK signaling by targeting miR-330-5p to promote non-small cell lung cancer progression.

Translational Lung Cancer Research, 2019
Background Circular RNAs (circRNAs) belong to a new type of endogenous non-coding RNA and plays a key role in carcinogenesis. Circ-ZKSCAN1 (hsa_circ_0001727) has been proven to be a tumor-dependent circRNA. However, its role in non-small cell lung cancer
Yuanyong Wang, Rongjian Xu, Dongyang Zhang, T. Lu, Wanpeng Yu, Yang Wo, Ao Liu, Tianyi Sui, Jian Cui, Yi Qin, Yanting Dong, X. Leng, Dezhi Kong, Wenxing Du, Zhangfeng Huang, Wenhao Su, Tianxiang Yuan, Xiao Sun, Jianxun Wang, W. Jiao   +19 more
semanticscholar   +1 more source

Power source, data retrieval method, and attachment type affect success of dorsally mounted tracking tag deployments in 37 species of shorebirds

Journal of Avian Biology, Volume 2025, Issue 6, November 2025.
Animal‐borne trackers are commonly used to study bird movements, including in long‐distance migrants such as shorebirds. Selecting a tracker and attachment method can be daunting, and methodological advancements often have been made by trial and error and conveyed by word of mouth.
Emily L. Weiser, Richard B. Lanctot, Daniel R. Ruthrauff, Sarah T. Saalfeld, T. Lee Tibbitts, José M. Abad‐Gómez, Joaquin Aldabe, Juliana Bosi de Almeida, José A. Alves, Guy Q.A. Anderson, Phil F. Battley, Heinrich Belting, Joël Bêty, Kristin Bianchini, Mary Anne Bishop, Roeland A. Bom, Katharine Bowgen, Glen S. Brown, Stephen C. Brown, Leandro Bugoni, Niall H.K. Burton, David R. Bybee, Camilo Carneiro, Gabriel Castresana, Ying‐Chi Chan, Chi‐Yeung Choi, Katherine S. Christie, Nigel A. Clark, Jesse R. Conklin, Medardo Cruz‐López, Stephen J. Dinsmore, Steve G. Dodd, David C. Douglas, Luke J. Eberhart‐Hertel, Willow B. English, Harry T. Ewing, Fernando A. Faria, Samantha E. Franks, Richard A. Fuller, Robert E. Gill Jr, Marie‐Andrée Giroux, Cheri L. Gratto‐Trevor, David J. Green, Rhys E. Green, Ros M.W. Green, Tómas G. Gunnarsson, Jorge S. Gutiérrez, Autumn‐Lynn Harrison, C. Alex Hartman, Chris J. Hassell, Sarah A. Hoepfner, Jos C. E. W. Hooijmeijer, James A. Johnson, Oscar W. Johnson, Bart Kempenaers, Marcel Klaassen, Eva M.A. Kok, Johannes Krietsch, Clemens Küpper, Andy Y. Kwarteng, Eunbi Kwon, Jean‐Francois Lamarre, Christopher J. Latty, Nicolas Lecomte, A.H. Jelle Loonstra, Zhijun Ma, Lucas Mander, Christopher Marlow, Peter P. Marra, Jose A. Masero, Laura A. McDuffie, Rebecca L. McGuire, Johannes Melter, David S. Melville, Verónica Méndez, Tyler J. Michels, Christy A. Morrissey, Tong Mu, David J. Newstead, Gary W. Page, Allison K. Pierce, Theunis Piersma, Márcio Repenning, Brian H. Robinson, Afonso D. Rocha, Danny I. Rogers, Amy L. Scarpignato, Shiloh Schulte, Emily S. Scragg, Nathan R. Senner, Paul A. Smith, Audrey R. Taylor, Rachel C. Taylor, Böðvar Þórisson, Mihai Valcu, Mo A. Verhoeven, Lena Ware, Nils Warnock, Michael F. Weber, Lucy J. Wright, Michael B. Wunder   +100 more
wiley   +1 more source

miR-330 Regulates Colorectal Cancer Oncogenesis by Targeting BACH1

Advanced Pharmaceutical Bulletin, 2020
Purpose: Based on WHO report, colorectal cancer (CRC) is the second cause of death among patients with cancer worldwide. Dysregulation of miRNAs expressions has been demonstrated in different human cancers, especially CRC. Studies have shown that miR-330
Solmaz Shirjang, B. Mansoori, A. Mohammadi, Neda Shajari, Pascal H G Duijf, S. Najafi, Fereydoon Abedi Gaballu, K. Nofouzi, B. Baradaran   +8 more
semanticscholar   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source