Results 31 to 40 of about 102,839 (113)

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Exposing the crumbling justification for absolute prosecutorial discretion in youth filing decisions

open access: yesFamily Court Review, Volume 63, Issue 3, Page 401-414, July 2025.
Abstract Can absolute prosecutorial discretion in youth charging decisions—like that allowed under Title 16 in the District of Columbia—continue to withstand legal, scientific, and policy‐based scrutiny? The recently‐approved Restatement of Children and the Law adds to the weight of authorities casting further doubt on the wisdom of such discretion ...
Nina A. Herth, Chinh Q. Le
wiley   +1 more source

Circ_0078767 suppresses non‐small‐cell lung cancer by protecting RASSF1A expression via sponging miR‐330‐3p

open access: yesCell Proliferation, 2018
This study was designed to investigate the role of circ_0078767/miR‐330‐3p/RASSF1A in non‐small‐cell lung cancer (NSCLC). Bioinformatic analysis was performed to screen for the differentially expressed genes in NSCLC tissues from adjacent lung tissues.
Ting Chen   +6 more
semanticscholar   +1 more source

Biomolecular Affinities and Cytotoxicity of Copper(I) and Silver(I) Phosphine–Pyridinyl Complexes Against CACO‐2 and CASKI Cell Lines

open access: yesEuropean Journal of Inorganic Chemistry, Volume 28, Issue 15, May 28, 2025.
This study reports Copper(I) and Silver(I) complexes with pyridinyl Schiff base ligands and triphenylphosphine. Their DNA/protein binding and in vitro cytotoxicity were evaluated. All complexes intercalated with calf thymus DNA, bound strongly to proteins, and showed notable cytotoxicity against Caco‐2 and Caski cancer cells, highlighting their promise
Adesola A. Adeleke   +4 more
wiley   +1 more source

Fluorene‐Arylamine Copolymers: Separable Control of Hole Transport and Light Emission Through Composition and Conformation

open access: yesJournal of Polymer Science, Volume 63, Issue 9, Page 2113-2121, 1 May 2025.
Copolymerization with arylamine initially reduces the mobility of the fluorene homopolymer due to trapping but increases with higher arylamine content, demonstrating that mobility in these copolymers is governed by chemical composition. While fluorene β‐phase conformation plays a minor role in transport, it strongly influences emission.
Nikol T. Lambeva   +3 more
wiley   +1 more source

HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Proinflammatory diseases, such as cancer, AIDS, and chronic obstructive pulmonary diseases, are often associated with a progressive loss of skeletal muscle tissue, a syndrome also known as cachexia.
Souad Mubaid   +12 more
semanticscholar   +1 more source

The pivotal role of mass spectrometry in transition metal‐based photocatalyst research for solar‐driven energy conversion and water purification advancements

open access: yesBulletin of the Korean Chemical Society, Volume 46, Issue 4, Page 381-412, April 2025.
This review explores recent advancements in the integration of solar energy conversion and water remediation with mass spectrometry as an analytical technique. We examine Ti‐based photocatalysts for their roles in energy conversion and water purification, utilizing mass spectrometric analysis to evaluate the efficiency of these mechanisms.
Haheun Yoo   +4 more
wiley   +1 more source

Opinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) relating to an analysis of the health risks associated with exposure to caterpillars with stinging hairs and the development of management recommendations

open access: yesFood Risk Assess Europe, Volume 3, Issue 2, April 2025.
Abstract Several species of Lepidoptera with caterpillars bearing urticating hairs are increasing their range in metropolitan France from year to year, such as the pine processionary (Thaumetopoea pityocampa Denis et Schiffermüller 1775) whose presence was historically limited to the south of France, and which is gradually being observed in the north ...
Nicolas Desneux   +105 more
wiley   +1 more source

Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis

open access: yesBritish Journal of Cancer, 2017
Background:MicroRNAs (miRs) are involved in the regulation of many processes that contribute to malignancy, including cell proliferation, radiation resistance, invasion and metastasis.
A. Mesci   +8 more
semanticscholar   +1 more source

Gene therapy for genetic diseases: challenges and future directions

open access: yesMedComm, Volume 6, Issue 2, February 2025.
The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie   +4 more
wiley   +1 more source

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