Results 101 to 110 of about 55,300 (116)

Pluchea dioscoridis extract: A novel therapeutic approach for polycystic ovary syndrome targeting ovarian morphology, dopamine pathways, and neurobehavior in relation to its phytocomponents. [PDF]

PLoS One
Atta R, Gouda SG, Mohamed MH, Afifi SM, Nassar MI, Farag MA, Elshamy AI, Zayed MA, Alqurashi T, Yousof SM.   +9 more
europepmc   +1 more source

Microglia contribute to methamphetamine reinforcement and reflect persistent transcriptional and morphological adaptations to the drug. [PDF]

Brain Behav Immun
Vilca SJ, Margetts AV, Höglund L, Fleites I, Bystrom LL, Pollock TA, Bourgain-Guglielmetti F, Wahlestedt C, Tuesta LM.   +8 more
europepmc   +1 more source

Decoding organ fibrosis: mechanistic insights and emerging therapeutic strategies. [PDF]

Signal Transduct Target Ther
Chen X, Zhang J, Guo L, Wu C, Zhou J, Xu M, Mo L, Li Y, He J.   +8 more
europepmc   +1 more source

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma. [PDF]

Front Pharmacol
Yao GS, Dai JS, Fu LM, Lin J, Tan ZP, Dai L, Chen W, Luo JH, Wei JH.   +8 more
europepmc   +1 more source

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Sphingomyelin-based PEGylation Cu(DDC)2 Liposomes Prepared via the Dual Function of Cu2+ for Cancer Therapy: Facilitating DDC Loading and Exerting Synergistic Antitumor Effects.

International journal of pharmaceutics, 2022
The old alcohol-aversion drug disulfiram (DSF) has aroused wide attention as a drug repurposing strategy in terms of cancer therapy because of the high antitumor efficacy in combination with copper ion.
Hao Liu, Yihan Kong, Zixu Liu, Xueting Guo, Binghua Yang, Tian Yin, Haibing He, Jingxin Gou, Yu Zhang, Xing Tang   +9 more
semanticscholar   +1 more source

Geniposide suppresses liver injury in a mouse model of DDC‐induced sclerosing cholangitis

Phytotherapy Research, 2021
Sclerosing cholangitis, characterized by biliary inflammation, fibrosis, and stricturing, remains one of the most challenging conditions of clinical hepatology. Geniposide (GE) has anti‐inflammatory, hepatoprotective, and cholagogic effects.
Min Wen, Yubei Liu, Ruiying Chen, P. He, Feihua Wu, Rui Li, Yining Lin   +6 more
semanticscholar   +1 more source

DDC: Dynamic duty cycle for improving delay and energy efficiency in wireless sensor networks

Journal of Network and Computer Applications, 2019
Due to the limit of computation and storage capability of devices, traditional security techniques face many challenges in the process of data transmission.
Yuxin Liu, Anfeng Liu, Ning Zhang, Xiao Liu, Mingchi Ma, Yanling Hu   +5 more
semanticscholar   +1 more source

Protective effect of herbal medicine Huangqi decoction against chronic cholestatic liver injury by inhibiting bile acid-stimulated inflammation in DDC-induced mice.

Phytomedicine, 2019
BACKGROUND Huangqi decoction (HQD), a classic traditional herbal medicine, has been used for liver fibrosis, but its effect on intrahepatic chronic cholestatic liver injury remains unknown.
Wenkai Li, Guofeng Wang, Tianming Wang, Yuan-yuan Li, Yi-fei Li, Xin Lu, Yahang Wang, Hua Zhang, Ping Liu, Jiasheng Wu, Yueming Ma   +10 more
semanticscholar   +1 more source

Long noncoding RNA MIAT regulates primary human retinal pericyte pyroptosis by modulating miR-342-3p targeting of CASP1 in diabetic retinopathy.

Experimental Eye Research, 2020
Diabetic retinopathy (DR) is the leading cause of visual impairment and acquired blindness among adults worldwide. Retinal microvascular pericyte deficiency is one of the earliest pathological changes associated with DR, and long noncoding RNA myocardial
Xinyang Yu, Xuefei Ma, Wenjian Lin, Qian Xu, Huan-Ran Zhou, H. Kuang   +5 more
semanticscholar   +1 more source

DDC-Outlier: Preventing Medication Errors Using Unsupervised Learning

IEEE journal of biomedical and health informatics, 2019
Electronic health records have brought valuable improvements to hospital practices by integrating patient information. In fact, the understanding of these data can prevent mistakes that may put patients’ lives at risk.
H. D. P. D. Santos, A. Ulbrich, Vinicius Woloszyn, Renata Vieira   +3 more
semanticscholar   +1 more source