Results 11 to 20 of about 55,300 (116)

LncRNA TP73‐AS1 promotes nasopharyngeal carcinoma progression through targeting miR-342-3p and M2 polarization via exosomes

Cancer Cell International, 2022
Background Nasopharyngeal carcinoma (NPC) is a deadly cancer, mainly presenting in southeast and east Asia. Long noncoding RNAs (lncRNAs) play essential roles in cancer progression. Exosomes are critical for intercellular communication.
Hongchao Yao, L. Tian, B. Yan, Like Yang, Yushan Li   +4 more
semanticscholar   +1 more source

Macrophage-derived exosomal miR-342-3p promotes the progression of renal cell carcinoma through the NEDD4L/CEP55 axis

Oncology Research, 2022
Due to its difficulty in early diagnosis and lack of sensitivity to chemotherapy and radiotherapy, renal cell carcinoma (RCC) remains to be a frequent cause of cancer-related death.
J. Feng, Beiping Xu, Chunmei Dai, Yaodong Wang, G. Xie, Wenyu Yang, Bingshu Zhang, Xiao-han Li, Jun Wang   +8 more
semanticscholar   +1 more source

Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease

Cells, 2022
Alzheimer’s disease (AD) is a common neurodegenerative disorder with progressive cognitive impairment in the elderly. Beta-amyloid (Aβ) formation and its accumulation in the brain constitute one of the pathological hallmarks of AD.
Zhiwu Dong, Hongjun Gu, Qiang Guo, Xianglu Liu, Feifei Li, Huiling Liu, Li Sun, Huimin Ma, Kewen Zhao   +8 more
semanticscholar   +1 more source

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1

Cell Death and Disease, 2022
Circular RNAs (circRNAs) can regulate autophagy and ovarian cancer (OC) progression. However, autophagy-associated circRNAs involved in OC progression are largely unknown.
Wenting Song, Zhirui Zeng, Yilei Zhang, Haili Li, Huimin Cheng, Jun Wang, Fengrui Wu   +6 more
semanticscholar   +1 more source

In Arabidopsis thaliana Cd differentially impacts on hormone genetic pathways in the methylation defective ddc mutant compared to wild type

Scientific Reports, 2021
DNA methylation plays an important role in modulating plant growth plasticity in response to stress, but mechanisms involved in such control need further investigation.
M. Pacenza, A. Muto, A. Chiappetta, L. Mariotti, E. Talarico, P. Picciarelli, E. Picardi, L. Bruno, M. B. Bitonti   +8 more
semanticscholar   +1 more source

Preclinical In Vitro Studies with 3D Spheroids to Evaluate Cu(DDC)2 Containing Liposomes for the Treatment of Neuroblastoma

Pharmaceutics, 2021
Preclinical in vitro studies of drug candidates for anticancer therapy are generally conducted on well-established 2D cell models. Unfortunately, these models are unable to mimic the properties of in vivo tumors.
F. Hartwig, M. Köll-Weber, R. Süss
semanticscholar   +1 more source

TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity

Cell Death and Disease, 2020
Growing evidences suggest that sustained neuroinflammation, caused by microglia overactivation, is implicated in the development and aggravation of several neurological and psychiatric disorders.
J. P. Brás, Joana Bravo, Jaime Freitas, M. Barbosa, S. Santos, T. Summavielle, M. Almeida   +6 more
semanticscholar   +1 more source

MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma.

Journal of Hepatology, 2020
BACKGROUND & AIMS Hepatocellular carcinoma (HCC) is a cancer with multiple etiologies, and widespread prevalence. Largely refractory to current treatments, HCC is the fourth leading cause of cancer related deaths, world-wide.
Ronja-Melinda Komoll, Q. Hu, Olaniyi Olarewaju, Lena von Döhlen, Q. Yuan, Yu Xie, H. Tsay, Joel Daon, R. Qin, M. Manns, Amar Deep Sharma, A. Goga, M. Ott, A. Balakrishnan   +13 more
semanticscholar   +1 more source

Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Plasma exosomes derived from healthy people have been shown to be beneficial in terms of protecting against ischemia-reperfusion injury or acute myocardial infarction (AMI).
Bo Wang, Chang Cao, Dongjian Han, Jing Bai, Jiacheng Guo, Qian-Qian Guo, Demin Li, Jianchao Zhang, Zenglei Zhang, Yunzhe Wang, Junnan Tang, Deliang Shen, Jinying Zhang   +12 more
semanticscholar   +1 more source

Hsa_circ_0004674 promotes osteosarcoma doxorubicin resistance by regulating the miR-342-3p/FBN1 axis

Journal of Orthopaedic Surgery and Research, 2021
Background The occurrence of chemoresistance is a common problem in tumor treatment. Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance.
Yu Bai, Yanghua Li, J. Bai, Yumei Zhang
semanticscholar   +1 more source