Results 11 to 20 of about 413 (67)

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]

MedComm (2020)
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G, Li F, Tang Y, Guo S, Yao Y, Fang Y, Zhang B, Jiang Y, Wang J, Wu D, Cheng J, Huang Z, Xin Z, Zhang T.   +13 more
europepmc   +2 more sources

Atopic dermatitis: pathogenesis and therapeutic intervention. [PDF]

MedComm (2020)
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease, and its complex pathogenesis is closely linked to genetic and environmental factors, skin barrier dysfunction as well as immune dysfunction, which imposes a significant socioeconomic burden in all countries. The compromised function of the skin barrier leads to the release of alarm
Yue C, Zhou H, Wang X, Yu J, Hu Y, Zhou P, Zhao F, Zeng F, Li G, Li Y, Feng Y, Sun X, Huang S, He M, Wu W, Huang N, Li J.   +16 more
europepmc   +2 more sources

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

High‐Entropy Magnetism of Murunskite

Advanced Functional Materials, Volume 35, Issue 40, October 1, 2025.
The study of murunskite (K2FeCu3S4) reveals that its magnetic and orbital order emerges in a simple I4/mmm crystal structure with complete disorder in the transition metal positions. Mixed‐valence Fe ions randomly occupy 1/4 of the tetrahedral sites, with the remaining 3/4 being filled by non‐magnetic Cu+ ions.
Davor Tolj, Priyanka Reddy, Ivica Živković, Luka Akšamović, Jian Rui Soh, Kamila Komȩdera, Izabela Biało, Naveen Kumar Chogondahalli Muniraju, Trpimir Ivšić, Mario Novak, Oksana Zaharko, Clemens Ritter, Thomas LaGrange, Wojciech Tabiś, Ivo Batistić, László Forró, Henrik M. Rønnow, Denis K. Sunko, Neven Barišić   +18 more
wiley   +1 more source

Framing consumer empowerment in the digital economy: From networks and engagement toward sustainable purchase

Business Ethics, the Environment &Responsibility, Volume 34, Issue 4, Page 1011-1032, October 2025.
Abstract The current study investigates the influence of variety among online providers and customers' access to knowledge on consumer networks, consumer engagement, and sustainable purchasing. Emphasis is on the underlying relationships among these constructs in the digital economy, which has evolved into a complex structure of multifarious nodes and ...
Elena‐Mădălina Vătămănescu, Elena Dinu, Patrizia Gazzola, Dan‐Cristian Dabija   +3 more
wiley   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Gene therapy for genetic diseases: challenges and future directions

MedComm, Volume 6, Issue 2, February 2025.
The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie, Jianghua Tuo, Feilong Chen, Haili Ding, Lei Lyu   +4 more
wiley   +1 more source