Results 21 to 30 of about 436 (68)

Gene therapy for genetic diseases: challenges and future directions

open access: yesMedComm, Volume 6, Issue 2, February 2025.
The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie   +4 more
wiley   +1 more source

Advancements of non‐invasive imaging technologies for the diagnosis and staging of liver fibrosis: Present and future

open access: yesVIEW, Volume 5, Issue 4, August 2024.
The authors provide an in‐depth exploration of recent advancements in ultrasound imaging, computed tomography imaging, magnetic resonance imaging, nuclear medicine imaging, radiomics, and artificial intelligence within the field of liver fibrosis research.
Wenpeng Huang, Yushuo Peng, Lei Kang
wiley   +1 more source

Coordination of a Phosphine‐Tethered Aminoborane to Group 10 Metals

open access: yesChemistry – A European Journal, Volume 30, Issue 32, June 6, 2024.
The synthesis and coordination chemistry of a diphosphine‐aminoborane ligand to group 10 metals is reported, affording a rare aminoborane π‐complex of Ni(0). The bonding situation is best described as a 3‐center‐4‐electron bond where the Ni and N atoms compete for an accepting orbital on boron.
Martine R. Tiddens   +4 more
wiley   +1 more source

Multiple genetic variants at the SLC30A8 locus affect local super‐enhancer activity and influence pancreatic β‐cell survival and function

open access: yesThe FASEB Journal, Volume 38, Issue 8, 30 April 2024.
GWAS‐identified SLC30A8 locus contains an islet super‐enhancer cluster. This super‐enhancer cluster regulates the expression of not only the SLC30A8 gene but also multiple other genes (UTP23, RAD21, MED30, and EXT1) which are involved in fundamental cellular machineries.
Ming Hu   +9 more
wiley   +1 more source

Opioid analgesia and severity of acute pancreatitis: An international multicentre cohort study on pain management in acute pancreatitis

open access: yesUnited European Gastroenterology Journal, Volume 12, Issue 3, Page 326-338, April 2024.
Abstract Background The effect of analgesic modalities on short‐term outcomes in acute pancreatitis remains unknown. However, preclinical models have raised safety concerns regarding opioid use in patients with acute pancreatitis. Objective This study aimed to assess the association between analgesics, particularly opioids, and severity and mortality ...
Sanjay Pandanaboyana   +372 more
wiley   +1 more source

Unwinding NFTs in the shadow of IP law

open access: yesAmerican Business Law Journal, Volume 61, Issue 1, Page 31-55, Spring 2024.
Abstract Amid the surge of intellectual property (IP) disputes surrounding non‐fungible tokens (NFTs), some scholars have advocated for the application of personal property or sales law to regulate NFT minting and transactions, contending that IP laws unduly hinder the development of the NFT market. This Article counters these proposals and argues that
Runhua Wang, Jyh‐An Lee, Jingwen Liu
wiley   +1 more source

Annual banned‐substance review 16th edition—Analytical approaches in human sports drug testing 2022/2023

open access: yesDrug Testing and Analysis, Volume 16, Issue 1, Page 5-29, January 2024.
Abstract In this 16th edition of the annual banned‐substance review on analytical approaches in human sports drug testing, literature on recent developments in this particular section of global anti‐doping efforts that was published between October 2022 and September 2023 is summarized and discussed.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

UEG Week 2025 Moderated Posters

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley   +1 more source

UEG Week 2025 Poster Presentations

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

Assessment of Hg pollution in stream waters and human health risk in areas impacted by mining activities in the Ecuadorian Amazon. [PDF]

open access: yesEnviron Geochem Health, 2023
Mestanza-Ramón C   +6 more
europepmc   +1 more source

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